6-Bromo-1H-indazole
Based on 1 Customer Validation
6-Bromo-1H-indazole is an indazole derivative that serves as an intermediate for research related to organic synthesis. 6-Bromo-1H-indazole acts as a building block for the preparation of PI3Kδ inhibitors, and also functions as a synthetic intermediate for the preparation of colchicine site-targeted tubulin polymerization inhibitors[1][2].
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- 純度 : 99.40%
- CAS 番号: 79762-54-2
- 分子式: C7H5BrN2
- 分子量:197.03
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保管条件:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
生物活性
製品説明
Cellular Effect
|
Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| Sf9 | IC50 |
1.1 μM
Compound: 7
|
Reversal inhibition of full length recombinant human MetAP2 expressed in baculovirus infected insect Sf9 cells using Met-AMC as substrate measured for 10 to 30 mins by fluorescence plate reader analysis
Reversal inhibition of full length recombinant human MetAP2 expressed in baculovirus infected insect Sf9 cells using Met-AMC as substrate measured for 10 to 30 mins by fluorescence plate reader analysis
|
[PMID: 27155900] |
体外実験
6-Bromo-1H-indazole serves as a synthetic building block for the preparation of PI3Kδ inhibitors[1].
6-Bromo-1H-indazole serves as a synthetic intermediate for the preparation of colchicine-site targeted tubulin polymerization inhibitors[2].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only. .
化学情報
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CAS 番号 79762-54-2
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性状 Solid
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分子量 197.03
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分子式 C7H5BrN2
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SMILES
BrC1=CC2=C(C=C1)C=NN2
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
純度とドキュメンテーション
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データシート (278 KB)
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取扱説明書 (2659 KB)
参考文献
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)