2. Neuronal Signaling Stem Cell/Wnt PI3K/Akt/mTOR Autophagy
  3. Monoamine Oxidase GSK-3 LRRK2
  4. Indazole

Indazole, also called isoindazole, a heterocyclic aromatic organic compound. Its derivatives display a broad variety of biological activities including anti-inflammatory, antibacterial, anti-HIV, antiarrhythmic, antifungal and antitumour properties. Indazole and its derivatives can be used for research of cancer, neurological disorders, cardiovascular diseases, gastrointestinal diseases.

For research use only. We do not sell to patients.

Indazole Chemical Structure

Indazole Chemical Structure

CAS No. : 271-44-3

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Indazole Related Antibodies

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Description

Indazole, also called isoindazole, a heterocyclic aromatic organic compound. Its derivatives display a broad variety of biological activities including anti-inflammatory, antibacterial, anti-HIV, antiarrhythmic, antifungal and antitumour properties. Indazole and its derivatives can be used for research of cancer, neurological disorders, cardiovascular diseases, gastrointestinal diseases[1][2][3][4][5].

In Vitro

Indazole compounds possess potential anticancer activity, and indazole-based agents such as, Axitinib (HY-10065) , Lonidamine (HY-B0486) and Pazopanib (HY-10208) have already been used for cancer research, demonstrating indazole compounds as useful templates for the development of novel anticancer agents[1].
Indazoles show potent activities against neurological disorders by inhibiting the monoamine oxidase (MAO) and kinase enzymes like Glycogen synthase kinase 3 (GSK3), and leucinerich repeat kinase enzyme 2 (LRRK2)[2].
Various natural and synthetic indazole derivatives Nigellicine, Nigellamine, Nigellidine, Zanubrutinib (HY-101474A) and SCH772984 (HY-50846) showes prominent results to cure various gastrointestinal disorders[4].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Indazole Related Antibodies
Molecular Weight

118.14

Formula

C7H6N2
CAS No.
Appearance

Solid

Color

Light brown to yellow

SMILES

C12=CC=CC=C1NN=C2
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Purity & Documentation

Purity: 99.72%

COA (248 KB)

Handling Instructions (2659 KB)
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Indazole Related Classifications

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Indazole271-44-3Monoamine OxidaseGSK-3LRRK2MAOGlycogen synthase kinase-3Glycogen synthase kinase 3Leucine-rich repeat kinase 2cancerneurological disorderscardiovascular diseasesgastrointestinal diseasesisoindazoleParkinson's diseaseAlzheimer's diseaseInhibitorinhibitorinhibit

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