207671-99-6
Chemical Structure
Benzoquinoquinoxaline
Synonym(s): BQQ
- CAS No.: 207671-99-6
- Formula:C23H21N5O
- Molecular Weight:383.45
IUPAC Name: N1-(11-methoxybenzo[f]quinolino[3,4-b]quinoxalin-6-yl)propane-1,3-diamine
InChIKey: VLYNNEGUOHUAER-UHFFFAOYSA-N
SMILES: NCCCNC1=NC2=C(C3=C1N=C(C=CC4=C5C=CC(OC)=C4)C5=N3)C=CC=C2
Biological Activity: Benzoquinoquinoxaline (BQQ) is a heterocyclic compound with an aminoalkyl side chain. Benzoquinoquinoxaline preferentially binds to DNA triplex structures, intercalates between the bases, thus, stabilising the triplex conformation. Conjugation of Benzoquinoquinoxaline to 1,10-phenanthroline specifically binds and cleaves double strand DNA at the site of formation of a triplex structure[1].
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Benzoquinoquinoxaline | 99.68% | Benzoquinoquinoxaline (BQQ) is a heterocyclic compound with an aminoalkyl side chain. Benzoquinoquinoxaline preferentially binds to DNA triplex structures, intercalates between the bases, thus, stabilising the triplex conformation. Conjugation of Benzoquinoquinoxaline to 1,10-phenanthroline specifically binds and cleaves double strand DNA at the site of formation of a triplex structure. | ||||||||||||||||||||
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