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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
24 Results for "
IL-12p40
" in MedChemExpress (MCE) Product Catalog:
Products (24)
24 Results for "IL-12p40" in MCE Product Catalog:
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1 Cited Publications
Cat. No.: HY-N3307
CAS No.: 40957-99-1
Cat. No.: HY-17028
CAS No.: 405165-61-9
Research Areas:
Besifloxacin Hydrochloride is a fourth generation fluoroquinolone antibiotic. Besifloxacin Hydrochloride is a DNA gyrase and topoisomerase IV inhibitor. Besifloxacin Hydrochloride has broad-spectrum antibacterial activity, it is effective against Gram-negative and Gram-positive aerobic and anaerobic strains and reduces the incidence of drug resistance. Besifloxacin Hydrochloride has anti-inflammatory activity. Besifloxacin Hydrochloride can be used in bacterial conjunctivitis research .
Cat. No.: HY-P990225
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Cat. No.: HY-N2495
CAS No.: 52250-35-8
Category:
Astragalus membranaceus var. mongholicus (Bunge)P.K.Hsiao Plants Other Flavonoids other families Flavonoids Leguminosae Phenols Polyphenols Disease Research Fields Inflammation/Immunology
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Cat. No.: HY-160231
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ssRNA42 (sodium) is a 20-mer phosphothioate protected single-stranded RNA oligonucleotide. ssRNA42 (sodium) derives from ssRNA40 by replacement of all G nucleotides with adenosine. ssRNA42 activated human PBMCs to secrete IFN-α, TNF-a, IL- 12p40, and IL-6, but ssRNA42 failed to stimulated murine pDCs and PBMCs.
Cat. No.: HY-123876
CAS No.: 2171502-44-4
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AS2677131 is a potent and orally active PIKfyve inhibitor. AS2677131 inhibits f IL-12p40, IL-6 and IL-1β through a PIKfyve-c-Rel pathway. AS2677131 selectively inhibits DNA-binding activity of c-Rel to IL-12p40 and IL-1β promoter. AS2677131 inhibits MHC class II expression on B cells. AS2677131 can be used for the researches of inflammation and immunology, such as arthritis .
Cat. No.: HY-177091
CAS No.: 2171506-45-7
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AS2795440 is a PIKfyve inhibitor. AS2795440 selectively inhibits proinflammatory cytokine such as IL-12p40 and IL-6 production and B cell activation without affecting Ca 2+ signaling. AS2795440 significantly reduces joint inflammation and bone loss in adjuvant-induced arthritis (AIA) mice model. AS2795440 can be used for inflammatory and autoimmune diseases like rheumatoid arthritis, psoriasis and inflammatory bowel disease research .
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Cat. No.: HY-153900
CAS No.: 2616605-55-9
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TLR8 agonist 6 (Compound A) is a TLR8 agonist, with an EC50 of 0.052 μM. TLR8 agonist 6 induces IL-12p40 production in human PBMC (EC50: 0.031 μM). TLR8 agonist 6 can be used in the research of virus resistance, infection resistance, autoimmunity, tumor, etc .
Cat. No.: HY-P991408
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Cat. No.: HY-N6250
CAS No.: 136087-29-1
Synonyms: Isomucronulatol 7-O-β-glucoside
Category:
Astragalus membranaceus var. mongholicus (Bunge)P.K.Hsiao Plants other families Flavonoids Monophenols Leguminosae Isoflavanones Phenols Disease Research Fields Inflammation/Immunology
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Cat. No.: HY-103295
CAS No.: 71800-36-7
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Cat. No.: HY-141454
CAS No.: 2412937-64-3
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TLR8 agonist 2 is a potent and selective TLR8 agonist with an EC50 of 3 nM for human TLR8. TLR8 agonist 2 shows less active against human TLR7 (EC50 of 33.33 μM) .
Cat. No.: HY-147375
CAS No.: 1870849-58-3
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Bromodomain inhibitor-10 (compound 128) is a potent bromodomain inhibitor with Kds of 15.0, 2500 nM for BRD4-1 and BRD4-2, respectively. Bromodomain inhibitor-10 inhibits the production of IL12p40 .
Cat. No.: HY-150729A
Purity: 98.78%
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ODN 1982 sodium is a unmethylated oligodeoxyribonucleotide (ODN) with no CpG motif, and can be used to prepare DNA vaccines. ODN 1982 sodium inhibits R-848 signaling. ODN 1982 sequence: 5’-tccaggacttctctcaggtt-3’ .
Cat. No.: HY-RS06681
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Il12b Mouse Pre-designed siRNA Set A contains three designed siRNAs for Il12b gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-N4061
CAS No.: 1383441-73-3
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Cat. No.: HY-128754R
CAS No.: 111-03-5
Synonyms: MG (18:1) (Standard)
Category:
Cat. No.: HY-141454A
CAS No.: 2412937-65-4
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TLR8 agonist 2 hydrochloride is a potent and selective TLR8 agonist with an EC50 of 3 nM for human TLR8. TLR8 agonist 2 hydrochloride shows less active against human TLR7 (EC50 of 33.33 μM) .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
