44 Results for "

Interleukin 1 alpha

" in MedChemExpress (MCE) Product Catalog:
Products (44)

44 Results for "Interleukin 1 alpha" in MCE Product Catalog:

10
10 Publications Verification
Cat. No.: HY-19975
CAS No.: 946387-07-1
Target:  

TRP Channel

Research Areas:  

Neurological Disease Cancer

RN-1734 is selective antagonist of the TRPV4 channel, completely antagonizes 4αPDD-mediated activation of TRPV4 with comparable, low micromolar IC50s for all three species (hTRPV4: 2.3 μM, mTRPV4: 5.9 μM, rTRPV4: 3.2 μM) . RN-1734 clearly decreases the production of tumor necrosis factor α (TNF-α) and interleukin 1β (IL-1β) without altering the number of olig2-positive cells .
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7
7 Cited Publications
Cat. No.: HY-P81232
Synonyms: caspase-1 isoform alpha subunit; CASP1; ICE; IL1BC; Caspase-1 subunit p20; CASP 1; Caspase 1 apoptosis related cysteine peptidase; Caspase 1 apoptosis related cysteine protease; Caspase1; IL 1 beta converting enzyme; IL 1BC; IL1B convertase; IL1BCE; Interleukin 1 beta convertase; Interleukin 1 beta convertase precursor; Interleukin 1 beta converting enzyme; CASP-1; Interleukin-1 beta convertase; IL-1BC; Interleukin-1 beta-converting enzyme; ICE; IL-1 beta-converting enzyme; p45; CASP1_HUMAN; CASP1_MOUSE.

Host:  

Rabbit

Application:  

WB, IHC-P, IHC-F, ICC/IF, FC

Reactivity:  

Human, Mouse, Rat

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5
5 Cited Publications
Cat. No.: HY-P7027
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: IL1A; IL-1A; Prev. IL1; PreInterleukin 1 alpha; IL1F1; Interleukin-1 alpha; Hematopoietin-1; IL-1 alpha; IL1-alpha; Interleukin 1 alpha; Pro-Interleukin-1-alpha
Species:  
Source:  
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2
2 Cited Publications
Cat. No.: HY-P7072
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: IL1A; IL-1A; Prev. IL1; PreInterleukin 1 alpha; IL1F1; Interleukin-1 alpha; Hematopoietin-1; IL-1 alpha; IL1-alpha; Interleukin 1 alpha; Pro-Interleukin-1-alpha
Species:  
Source:  
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1
1 Cited Publications
Cat. No.: HY-P7096
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: IL1A; IL-1A; Prev. IL1; PreInterleukin 1 alpha; IL1F1; Interleukin-1 alpha; Hematopoietin-1; IL-1 alpha; IL1-alpha; Interleukin 1 alpha; Pro-Interleukin-1-alpha
Species:  
Rat
Source:  
CHO
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1
1 Cited Publications
Cat. No.: HY-P73145
Purity:  ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: IL1A; IL-1A; Prev. IL1; PreInterleukin 1 alpha; IL1F1; Interleukin-1 alpha; Hematopoietin-1; IL-1 alpha; IL1-alpha; Interleukin 1 alpha; Pro-Interleukin-1-alpha
Species:  
Source:  
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1
1 Cited Publications
Cat. No.: HY-P70702
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: IL36A; Interleukin-1 Epsilon; Prev. IL1F6; FIL1 Epsilon; IL-1F6; IL-1 Epsilon; FIL1E; MGC129553; IL1(EPSILON); MGC129552; FIL1; IL-1F6 (FIL-1-Epsilon); Interleukin 1 Family, Member 6 (Epsilon); FIL1(EPSILON); Interleukin-1 Family Member 6; IL1E; Interleuk
Species:  
Source:  
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Cat. No.: HY-P99246
CAS No.: 1401965-15-8
Synonyms: MABp1

Target:  

Interleukin Related

Research Areas:  

Inflammation/Immunology Cancer

Bermekimab (MABp1) is a human monoclonal antibody targeting interleukin-1α(IL-1α) . Bermekimab can prevent tumor-related inflammation. Bermekimab can be used in the research of atopic dermatitis .
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Cat. No.: HY-W852084
CAS No.: 151751-58-5
Target:  

Drug Derivative

Research Areas:  

Infection Cancer

S-27609 is an imidazoquinoline with antiviral and antitumour properties. S-27609 can induce peripheral blood mononuclear cells to produce various cytokines such as interferon-α (IFN-α), tumor necrosis factor-α (TNF-α), and interleukin-1β (IL-1β). S-27609 is promising for research of viral infections (e.g., herpes virus) and tumors .
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Cat. No.: HY-155027
DPP-4-IN-8 (compound 27) is a potent and selective DPP4 (dipeptidyl peptidase 4) inhibitor, with a Ki of 0.96 μM. DPP-4-IN-8 blocks the dipeptidase activity of DPP4 in both Caco-2 and HepG-2 cells. DPP-4-IN-8 also dose-dependently suppresses the expression levels of the chemokines tumor necrosis factor-α (TNF-α), interleukin-6 (IL-6), and interleukin-1β (IL-1β) .
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Cat. No.: HY-N1120
CAS No.: 142937-50-6
Synonyms: (+)-Triptoquinone B
Triptoquinone B ((+)-Triptoquinone B), a sesquiterpene alkaloid, is an interleukin-1 inhibitor. Triptoquinone B shows potent inhibitory activities against interleukin 1α and β releases for human peripheral mononuclear cells .
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Cat. No.: HY-174628
Target:  

mRNA

Research Areas:  

Inflammation/Immunology

Human IL1A mRNA encodes the human interleukin 1 alpha (IL1A) protein, a member of the interleukin 1 cytokine family. IL1A is a pleiotropic cytokine involved in various immune responses, inflammatory processes, and hematopoiesis.
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Cat. No.: HY-N12837
CAS No.: 79172-04-6
8-Epiloganin can be isolated from Castilleja rubra and has anti-inflammatory properties. 8-Epiloganin inhibits LPS-induced release of pro-inflammatory cytokines, namely tumor necrosis factor-α and interleukin-1β .
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Cat. No.: HY-126758
CAS No.: 36149-87-8
Ludartin a sesquiterpene lactone, which can be isolated from the plant Artemisia carruthii Wood. Ludartin reduces the expression of myeloperoxidase and malondialdehyde, enhances the expression of glutathione and superoxide dismutase in spinal cord tissue. Ludartin inhibits neuronal apoptosis. Ludartin inhibits the upregulation of tumor necrosis factor-α, interleukin-1β, and interleukin-6. Ludartin improves the motor function of rats with spinal cord injury .
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Cat. No.: HY-N8936
CAS No.: 1356822-09-7
Narchinol B (Compound 4) is a sesquiter penoid compound. Narchinol B has anti-inflammatory effects. Narchinol B works by inhibiting proinflammatory mediators, including prostaglandin E2 (PGE2), inducible nitric oxide synthase (iNOS), and cyclooxygenase-2 (COX-2) proteins, as well as proinflammatory cytokines, such as interleukin-1b, IL-6, and tumor necrosis factor-α (TNF-α). Narchinol B significantly inhibits LPS-induced overproduction of NO in BV2 cells (IC50=2.43 μM) .
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Cat. No.: HY-174630
Target:  

mRNA

Research Areas:  

Inflammation/Immunology

Human IL18R1 mRNA encodes the human interleukin 18 receptor 1 (IL18R1) protein, a cytokine receptor that belongs to the interleukin 1 receptor family. IL18R1 is essential for IL18 mediated signal transduction. IFN-alpha and IL12 are reported to induce the expression of this receptor in NK and T cells.
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Cat. No.: HY-P81115
Synonyms: Interleukin-1 alpha; Hematopoietin 1; IL 1 alpha; IL1 alpha; IL 1; IL 1A; Il-1a; IL1; IL1A; IL1F1; ilia; Interleukin 1 alpha; Interleukin 1 alpha precursor; Interleukin1 alpha; PreInterleukin 1 alpha; Pro Interleukin 1 alpha; ProInterleukin 1 alpha; IL1A_HUMAN.

Host:  

Rabbit

Application:  

WB, ELISA, IHC-P, IHC-F, FC, IF-Tissue

Reactivity:  

Human, Mouse

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Cat. No.: HY-P74823
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: IL1R1; IL-1R-alpha; Prev. IL1RA; Interleukin 1 Receptor alpha, Type I; Prev. IL1R; Interleukin-1 Receptor, Type I; CD121 Antigen-Like Family Member A; Interleukin 1 Receptor, Type I; Interleukin-1 Receptor Type 1; CD121a Antigen; Interleukin-1 Receptor Ty
Species:  
Source:  
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Cat. No.: HY-P70286
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: IL1R1; IL-1R-alpha; Prev. IL1RA; Interleukin 1 Receptor alpha, Type I; Prev. IL1R; Interleukin-1 Receptor, Type I; CD121 Antigen-Like Family Member A; Interleukin 1 Receptor, Type I; Interleukin-1 Receptor Type 1; CD121a Antigen; Interleukin-1 Receptor Ty
Species:  
Source:  
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Cat. No.: HY-P72569
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: IL1R1; IL-1R-alpha; Prev. IL1RA; Interleukin 1 Receptor alpha, Type I; Prev. IL1R; Interleukin-1 Receptor, Type I; CD121 Antigen-Like Family Member A; Interleukin 1 Receptor, Type I; Interleukin-1 Receptor Type 1; CD121a Antigen; Interleukin-1 Receptor Ty
Species:  
Source:  
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