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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
14 Results for "
LOX inhibitory
" in MedChemExpress (MCE) Product Catalog:
Products (14)
14 Results for "LOX inhibitory" in MCE Product Catalog:
Cat. No.: HY-N2176
CAS No.: 13849-08-6
Synonyms: (+)-Marmesin; (S)-Marmesin
Category:
Other Diseases Coumarins Phenylpropanoids Plants Umbelliferae Disease Research Fields Bidens parviflora Willd.
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Cat. No.: HY-W020955
CAS No.: 14243-64-2
Synonyms: Chloro(triphenylphosphine)gold(I)
Cat. No.: HY-W009248
CAS No.: 71835-85-3
Category:
Monophenols Phenols Plants Umbelliferae Kleinia odora (Forssk.) DC. Disease Research Fields Inflammation/Immunology
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Cat. No.: HY-W041193
CAS No.: 496-64-0
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Cat. No.: HY-106835
CAS No.: 112344-52-2
Synonyms: VUFB 16066
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Research Areas:
Flobufen (VUFB 16066) is a non-steroidal anti-inflammatory agent and cyclooxygenase (COX) and 5-lipoxygenase (5-LOX) inhibitor agent. Flobufen inhibits alloantigen-driven cellular immune responses and stimulates phagocytosis of peritoneal cells. Flobufen can improve immunopathological disorders and has an inhibitory effect on rheumatoid arthritis .
Cat. No.: HY-N8764
CAS No.: 61548-34-3
Synonyms: Decaffeoylverbascoside; Verbasoside
Category:
Cat. No.: HY-N2266
CAS No.: 130783-32-3
Category:
Lignans Phenylpropanoids Plants Schisandraceae Disease Research Fields Inflammation/Immunology Schisandra chinensis (Turcz.) Baill.
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Cat. No.: HY-N2176R
CAS No.: 13849-08-6
Synonyms: (+)-Marmesin (Standard); (S)-Marmesin (Standard)
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Cat. No.: HY-146294
CAS No.: 2410384-50-6
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Research Areas:
COX-2/5-LOX-IN-1 (compound 3a) is a potent and dual inhibitor of COX-2/5-LOX. COX-2/5-LOX-IN-1 is a benzothiophen-2-yl pyrazole carboxylic acid derivative. COX-2/5-LOX-IN-1 shows the most potent analgesic and anti-inflammatory activities surpassing that of Celecoxib and Indomethacin. COX-2/5-LOX-IN-1 shows potent COX-1, COX-2 and 5-LOX inhibitory activity with IC50s of 12.13, 0.4 and 4.96 μM, respectively .
Cat. No.: HY-146295
CAS No.: 2410384-59-5
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Research Areas:
COX-2/5-LOX-IN-2 (5b) is a potent and dual inhibitor of COX-2/5-LOX. COX-2/5-LOX-IN-2 is a benzothiophen-2-yl pyrazole carboxylic acid derivative. COX-2/5-LOX-IN-2 shows the most potent analgesic and anti-inflammatory activities surpassing that of Celecoxib and Indomethacin. COX-2/5-LOX-IN-2 shows potent COX-1, COX-2 and 5-LOX inhibitory activity with IC50s of 5.40, 0.01 and 1.78 μM, respectively .
Cat. No.: HY-114796
CAS No.: 43230-43-9
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Research Areas:
tHGA is a compound with anti-inflammatory activity and has the activity to inhibit soybean 15-LOX. tHGA showed significant inhibitory effects in experiments on human leukocytes, with an IC50 value of 0.42 μM, which is close to the effect of commonly used standard NDGA. tHGA concentration-dependently inhibits the synthesis of 5-LOX products, especially the cysteine leukotriene LTC(4), with an IC50 value of 1.80 μM. and showed no cytotoxicity. The anti-inflammatory effects of tHGA do not appear to be through redox or metal chelation mechanisms, as the compound was negative in these bioactivity tests. tHGA works through a dual LOX/COX inhibition mechanism and has higher selectivity for 5-LOX and COX-2, with an IC50 value of 0.40 μM .
Cat. No.: HY-180363
CAS No.: 120164-49-0
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Research Areas:
E 6080 is an orally active and selective 5-lipoxygenase (5-LOX) inhibitor with an IC50 of 0.2 μM in rat basophilic leukemia cell. E 6080 shows potent inhibitory effects on the release of leukotrienes. E 6080 inhibits the bronchospasm induced by antigen (ovalbumin) inhalation in sensitized conscious guinea pigs. E 6080 can be used for the study of asthma .
Cat. No.: HY-N16694
CAS No.: 34539-84-9
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
