COX-2/5-LOX-IN-1
COX-2/5-LOX-IN-1 (compound 3a) is a potent and dual inhibitor of COX-2/5-LOX. COX-2/5-LOX-IN-1 is a benzothiophen-2-yl pyrazole carboxylic acid derivative. COX-2/5-LOX-IN-1 shows the most potent analgesic and anti-inflammatory activities surpassing that of Celecoxib and Indomethacin. COX-2/5-LOX-IN-1 shows potent COX-1, COX-2 and 5-LOX inhibitory activity with IC50s of 12.13, 0.4 and 4.96 μM, respectively.
For research use only. We do not sell to patients.
- CAS No.: 2410384-50-6
- Formula: C14H10ClN3O4S2
- Molecular Weight:383.83
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Chemical Information
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CAS No. 2410384-50-6
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Molecular Weight 383.83
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Formula C14H10ClN3O4S2
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SMILES
OC(C1=NN(C(C2=CC=C(S2)Cl)=C1)C3=CC=C(C=C3)S(N)(=O)=O)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
COX-2/5-LOX-IN-1 Related Classifications
HY-146294 Related Classifications
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