COX-2/5-LOX-IN-2
COX-2/5-LOX-IN-2 (5b) is a potent and dual inhibitor of COX-2/5-LOX. COX-2/5-LOX-IN-2 is a benzothiophen-2-yl pyrazole carboxylic acid derivative. COX-2/5-LOX-IN-2 shows the most potent analgesic and anti-inflammatory activities surpassing that of Celecoxib and Indomethacin. COX-2/5-LOX-IN-2 shows potent COX-1, COX-2 and 5-LOX inhibitory activity with IC50s of 5.40, 0.01 and 1.78 μM, respectively.
For research use only. We do not sell to patients.
- CAS No.: 2410384-59-5
- Formula: C18H13N3O4S2
- Molecular Weight:399.44
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Chemical Information
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CAS No. 2410384-59-5
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Molecular Weight 399.44
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Formula C18H13N3O4S2
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SMILES
OC(C1=NN(C(C2=CC3=C(S2)C=CC=C3)=C1)C4=CC=C(C=C4)S(N)(=O)=O)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
COX-2/5-LOX-IN-2 Related Classifications
HY-146295 Related Classifications
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