496-64-0
496-64-0
Chemical Structure
3-Hydroxy-2-pyrone
- CAS No.: 496-64-0
- Formula:C5H4O3
- Molecular Weight:112.08
IUPAC Name: 3-hydroxy-2H-pyran-2-one
InChIKey: LIPRKYKMVQPYPG-UHFFFAOYSA-N
SMILES: O=C1OC=CC=C1O
Biological Activity: 3-Hydroxy-2-pyrone (Compound 12d) is a metalloenzyme inhibitor. 3-Hydroxy-2-pyrone shows an inhibition rate of approximately 50% for matrix metalloproteinases (MMP) and the inhibition rate for non-heme iron enzyme 5-lipoxygenase (5-LOX) was over 70% at 1 mM. 3-Hydroxy-2-pyrone also has certain inhibitory activity against copper-dependent enzyme tyrosinase. 3-Hydroxy-2-pyrone can be used for the research of cancer, infection and inflammation[1].
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3-Hydroxy-2-pyrone | 3-Hydroxy-2-pyrone (Compound 12d) is a metalloenzyme inhibitor. 3-Hydroxy-2-pyrone shows an inhibition rate of approximately 50% for matrix metalloproteinases (MMP) and the inhibition rate for non-heme iron enzyme 5-lipoxygenase (5-LOX) was over 70% at 1 mM. 3-Hydroxy-2-pyrone also has certain inhibitory activity against copper-dependent enzyme tyrosinase. 3-Hydroxy-2-pyrone can be used for the research of cancer, infection and inflammation. | |||||||||||||||||||||
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