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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
10 Results for "
LXR antagonist
" in MedChemExpress (MCE) Product Catalog:
Products (10)
10 Results for "LXR antagonist" in MCE Product Catalog:
37
37 Cited Publications
Target:
Forschungsgebiete:
GSK2033 is a LXR antagonist with pIC50s of 7 and 7.4 for LXRα or LXRβ, respectively.
Art. -Nr.: HY-W002314
CAS. Nr.: 2491-38-5
Forschungsgebiete:
2-Bromo-4'-hydroxyacetophenone is a PTP1B inhibitor with a Ki value of 42 μM. 2-Bromo-4'-hydroxyacetophenone is also an intermediate. 2-Bromo-4'-hydroxyacetophenone can be used in the synthesis of LXRα/β antagonists. 2-Bromo-4'-hydroxyacetophenone can be used in research on hematological diseases .
Art. -Nr.: HY-139576B
Reinheit: ≥97.0%
Synonyms: DUR-928 trimethylamine
Target:
Art. -Nr.: HY-139576
CAS. Nr.: 884905-07-1
Synonyms: DUR-928
Target:
Art. -Nr.: HY-N2273
CAS. Nr.: 19942-02-0
Category:
Triterpenes Terpenoids Asclepiadaceae Metabolic Disease Plants Disease Research Fields Gymnema sylvestre (Retz.) Schult.
Target:
Art. -Nr.: HY-134969
CAS. Nr.: 895700-18-2
Target:
Forschungsgebiete:
TFCA is a liver X receptor α (LXRα) antagonist. TFCA inhibits ligand-activated LXRα coactivation and transcriptional expression of the downstream target genes involved in fatty acid synthesis. TFCA attenuates ligand-induced lipogenesis and fatty liver by selectively inhibiting LXRα in the liver .
Art. -Nr.: HY-170570
CAS. Nr.: 3053859-57-4
Forschungsgebiete:
PFM046 is the antagonist for liver X receptor (LXR), that inhibits the activation of LXRα and LXRβ with IC50 of 2.04 μM and 1.58 μM. PFM046 inhibits the expression of SCD1 and FASN, upregulates the expression of ABCA1, and exhibits antitumor efficacy in mouse models .
Art. -Nr.: HY-139576C
CAS. Nr.: 2655654-16-1
Synonyms: DUR-928 ammonium
Target:
Forschungsgebiete:
Larsucosterol (DUR-928) ammonium, a cholesterol metabolite, is a potent liver X receptor (LXR) antagonist. Larsucosterol ammonium as a potent endogenous regulator decreases lipogenesis. Larsucosterol ammonium inhibits the cholesterol biosynthesis via decreasing mRNA levels and inhibiting the activation of SREBP-1 .
Art. -Nr.: HY-139576A
CAS. Nr.: 1174047-40-5
Synonyms: DUR-928 sodium
Target:
Art. -Nr.: HY-108688R
CAS. Nr.: 1221277-90-2
Target:
Forschungsgebiete:
GSK2033 (Standard) is the analytical standard of GSK2033 (HY-108688). This product is intended for research and analytical applications. GSK2033 is a LXR antagonist with pIC50s of 7 and 7.4 for LXRα or LXRβ, respectively.
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
