2491-38-5
2491-38-5
Chemical Structure
2-Bromo-4'-hydroxyacetophenone
- CAS No.: 2491-38-5
- Formula:C8H7BrO2
- Molecular Weight:215.05
IUPAC Name: 2-bromo-1-(4-hydroxyphenyl)ethan-1-one
InChIKey: LJYOFQHKEWTQRH-UHFFFAOYSA-N
SMILES: OC1=CC=C(C(CBr)=O)C=C1
Biological Activity: 2-Bromo-4'-hydroxyacetophenone is a PTP1B inhibitor with a Ki value of 42 μM. 2-Bromo-4'-hydroxyacetophenone is also an intermediate. 2-Bromo-4'-hydroxyacetophenone can be used in the synthesis of LXRα/β antagonists. 2-Bromo-4'-hydroxyacetophenone can be used in research on hematological diseases[1][2].
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2-Bromo-4'-hydroxyacetophenone | 98.57% | 2-Bromo-4'-hydroxyacetophenone is a PTP1B inhibitor with a Ki value of 42 μM. 2-Bromo-4'-hydroxyacetophenone is also an intermediate. 2-Bromo-4'-hydroxyacetophenone can be used in the synthesis of LXRα/β antagonists. 2-Bromo-4'-hydroxyacetophenone can be used in research on hematological diseases. | ||||||||||||||||||||
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References
- [1]. Sidhu, Alban, et al. Toward Inhibitors of Protein Tyrosine Phosphatases for Cancer Treatment. Home / Current Enzyme Inhibition, Volume 4, Number 1.
- [2]. Nian S, et al. Discovery and Synthesis of a Novel Series of Liver X Receptor Antagonists. Chem Pharm Bull (Tokyo). 2015;63(8):628-35. [Content Brief]
