2 Results for "

LY2922470

" in MedChemExpress (MCE) Product Catalog:
Products (2)

2 Results for "LY2922470" in MCE Product Catalog:

  • Targets Recommended:
1
1 Cited Publications
Cat. No.: HY-19835
CAS No.: 1423018-12-5
Research Areas:  

Metabolic Disease

LY2922470 is a selective and orally active agonist for the G protein-coupled receptor 40 (GPR40). LY2922470 activates GPR40-mediated β-arrestin recruitment with EC50s of 7 nM (human GPR40), 1 nM (mouse GPR40) and 3 nM (rat GPR40). LY2922470 can be used for research of type 2 diabetes mellitus (T2DM) .
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Cat. No.: HY-117978
CAS No.: 1309435-78-6
Research Areas:  

Endocrinology

LY2922083 and related compounds LY2881835 and LY2922470 are spiperidine and tetrahydroquinolinic acid derivatives that are potent GPR40 agonists. LY2922083 activates GPR40 in response to elevated blood glucose and has the potential to be a glucose-lowering agent .
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