2. Search Result
Search Result
Results for "

Lck-IN-1

" in MedChemExpress (MCE) Product Catalog:

6

Inhibitors & Agonists

1

Fluorescent Dyes

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-138202
    Lck-IN-1

    		Src Inflammation/Immunology
    Lck-IN-1 is a potent lymphocyte protein tyrosine kinase (Lck) inhibitor extracted from patent WO2007013673A1, example 48 [1].
    Lck-IN-1
  • HY-175280
    Lck degrader-1

    		Molecular Glues Src Cancer
    Lck degrader-1 (Compound 17) is a molecular glue degrader targeting lymphocyte-specific protein tyrosine kinase (LCK) (DC50=23.1 nM). Lck degrader-1 is promising for research of T-cell acute lymphoblastic leukemia (T-ALL) [1].
    Lck degrader-1
  • HY-160151
    TP1L

    		PROTACs Phosphatase JAK IFNAR MHC Cancer
    TP1L is a potent and selective T-cell protein tyrosine phosphatase (TC-PTP) PROTAC degrader, with a DC50 value of 35.8 nM. TP1L elevates the phosphorylation level of TC-PTP substrates including pSTAT1 and pJAK1. TP1L selectively enhances IFN-γ signaling and increases MHC-I expression. TP1L activates TCR signaling through increases phosphorylation of LCK. TP1L enhances CAR-T cell mediated tumor killing efficacy through activation of the CAR-T cells. TP1L can be used for the study of cancer. (Pink: TC-PTP ligand: (HY-138964), Blue: E3 ligase CRBN Ligand (HY-A0003), Black: Linker: (HY-140002)) [1].
    TP1L
  • HY-170365
    HPK1-IN-55

    		MAP4K Inflammation/Immunology Cancer
    HPK1-IN-55 (compound 19) is a selective and orally active hematopoietic progenitor kinase 1 (HPK1) inhibitor with an IC50 of <0.51 nM. HPK1-IN-55 shows excellent kinase selectivity (>637-fold vs GCK-like kinase and >1022-fold vs LCK). HPK1-IN-55 has anticancer effects [1].
    HPK1-IN-55
  • HY-D3058
    FITC-amide-C2 Lck inhibitor 2

    		Src Fluorescent Dye Others
    FITC-amide-C2 Lck inhibitor 2 is a FITC-labeled Lck inhibitor .
    FITC-amide-C2 Lck inhibitor 2
  • HY-175916
    LCK ligand-1

    		Ligands for Target Protein for PROTAC Src Cancer
    LCK ligand-1 is a ligand targeting LCK, which serves as a target protein ligand for the synthesis of the PROTAC degrader SJ45566 (HY-162676) [1].
    LCK ligand-1

Inquiry Online

Your information is safe with us. * Required Fields.

Salutation

  

Country or Region *

Applicant Name *

 

Organization Name *

Department *

     

Email Address *

 

Product Name *

Cat. No.

  

Requested quantity *

Phone Number *

     

Remarks

Inquiry Online

Inquiry Information

Product Name:
Cat. No.:
Quantity:
MCE Japan Authorized Agent: