3095033-62-5

Lck degrader-1 Chemical Structure
3095033-62-5

Chemical Structure

Lck degrader-1

  • CAS No.: 3095033-62-5
  • Formula:C25H25N5O4
  • Molecular Weight:459.50

IUPAC Name: 7-(aminomethyl)-N-(2-(2,6-dioxopiperidin-3-yl)-1-oxoisoindolin-5-yl)-3-ethyl-1H-indole-2-carboxamide

InChIKey: KMGBAFLISYQLRW-UHFFFAOYSA-N

SMILES: CCC1=C(NC2=C1C=CC=C2CN)C(NC3=CC4=C(C(N(C5CCC(NC5=O)=O)C4)=O)C=C3)=O

Biological Activity: Lck degrader-1 (Compound 17) is a molecular glue degrader targeting lymphocyte-specific protein tyrosine kinase (LCK) (DC50=23.1 nM). Lck degrader-1 is promising for research of T-cell acute lymphoblastic leukemia (T-ALL)[1].

Cat. No. Product Name Purity Description Pricing
HY-175280 		Lck degrader-1 Lck degrader-1 (Compound 17) is a molecular glue degrader targeting lymphocyte-specific protein tyrosine kinase (LCK) (DC50=23.1 nM). Lck degrader-1 is promising for research of T-cell acute lymphoblastic leukemia (T-ALL).
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