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Cat. No.: HY-175916

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LCK ligand-1

LCK ligand-1 is a ligand targeting LCK, which serves as a target protein ligand for the synthesis of the PROTAC degrader SJ45566 (HY-162676).

For research use only. We do not sell to patients.

CAS No.: 823206-99-1
Formula: C₁₆H₁₄ClN₅OS
Molecular Weight:359.83

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

LCK ligand-1 Chemical Structure

CAS No.: 823206-99-1

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- IC₅₀ & Target
Chemical Information
Purity & Documentation
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

Description

LCK ligand-1 is a ligand targeting LCK, which serves as a target protein ligand for the synthesis of the PROTAC degrader SJ45566 (HY-162676)^[1].

IC₅₀ & Target^[1]

Lck

All Src Isoforms :

Chemical Information

CAS No. 823206-99-1
Molecular Weight 359.83
Formula C₁₆H₁₄ClN₅OS
SMILES

O=C(NC1=C(Cl)C=CC=C1C)C(S2)=CN=C2NC3=CC=NC(C)=N3
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Handling Instructions (2659 KB)

References

[1]. Chen X, et al. Mighty mini-PROTACs: an emerging class of degraders. Eur J Med Chem. 2026;301:118202. [Content Brief]

Calculators

Molarity Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Dilution Calculator

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Keywords

100 mg

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