2 Results for "

Licochalcone B (Standard)

" in MedChemExpress (MCE) Product Catalog:
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2 Results for "Licochalcone B (Standard)" in MCE Product Catalog:

Licochalcone B (Standard)
Licochalcone B (Standard)
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Cat. No.: HY-N0373R
CAS No.: 58749-23-8
Category:  

Flavonoids Chalcones Leguminosae Phenols Polyphenols Plants Glycyrrhiza uralensis Fisch.

Target:  

Reference Standards Amyloid-β Apoptosis NOD-like Receptor (NLR)

Licochalcone B (Standard) is the analytical standard of Licochalcone B. This product is intended for research and analytical applications. Licochalcone B is an extract from the root of Glycyrrhiza uralensis. Licochalcone B inhibits amyloid β (42) self-aggregation (IC50=2.16 μM) and disaggregate pre-formed Aβ42 fibrils, reduce metal-induced Aβ42 aggregation through chelating metal ionsLicochalcone B inhibits phosphorylation of NF-κB p65 in LPS signaling pathway. Licochalcone B inhibits growth and induces apoptosis of NSCLC cells. Licochalcone B specifically inhibits the NLRP3 inflammasome by disrupting NEK7‐NLRP3 interaction .
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Licochalcone A (Standard)
Licochalcone A (Standard)
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Cat. No.: HY-N0372R
CAS No.: 58749-22-7
Category:  

Flavonoids Chalcones Leguminosae Plants Glycyrrhiza uralensis Fisch.

Target:  

Reference Standards Autophagy

Licochalcone A (Standard) is the analytical standard of Licochalcone A (HY-N0372). This product is intended for research and analytical applications. Licochalcone A (LCA), a chalconoid, presents obvious anti-cancer effects, displays broad-spectrum inhibition against UDP-glucuronosyltransferases (UGTs) . Licochalcone A (LCA) exhibits strong inhibitory effects against UGT1A1, 1A3, 1A4, 1A6, 1A7, 1A9, and 2B7 (both IC50 and Ki values lower than 5 μM) .
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