6 Results for "

Lumacaftor

" in MedChemExpress (MCE) Product Catalog:
Products (6)

6 Results for "Lumacaftor" in MCE Product Catalog:

21
21 Cited Publications
Cat. No.: HY-13262
CAS No.: 936727-05-8
Purity:  99.85%
Synonyms: VX-809; VRT 826809
Target:  

CFTR Autophagy

Research Areas:  

Inflammation/Immunology

Lumacaftor (VX-809; VRT 826809) is a CFTR modulator that corrects the folding and trafficking of CFTR protein.
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Cat. No.: HY-115878
CAS No.: 2858812-70-9
Purity:  98.87%
Target:  

CFTR

Research Areas:  

Others

NJH-2-057 is an EN523 OTUB1 recruiter linked to lumacaftor, a agent used to treat cystic fibrosis that binds ΔF508-CFTR.
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Cat. No.: HY-143344
CAS No.: 2858812-69-6
Purity:  98.23%
Target:  

DUBTACs CFTR

Research Areas:  

Inflammation/Immunology

NJH-2-056 is a deubiquitinase-targeting chimera (DUBTAC) linking the OTUB1 recruiter EN523 to the CFTR chaperone lumacaftor. NJH-2-056 can be used for cystic fibrosis research .
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Cat. No.: HY-13262S
CAS No.: 2733561-44-7
Purity:  99.84%
Synonyms: VX-809-d4; VRT 826809-d4
Lumacaftor-d4 is the deuterium labeled Lumacaftor (HY-13262) .
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Cat. No.: HY-13262R
CAS No.: 936727-05-8
Synonyms: VX-809 (Standard); VRT 826809 (Standard)
Research Areas:  

Inflammation/Immunology

Lumacaftor (Standard) is the analytical standard of Lumacaftor. This product is intended for research and analytical applications. Lumacaftor (VX-809; VRT 826809) is a CFTR modulator that corrects the folding and trafficking of CFTR protein.
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Cat. No.: HY-161894
Target:  

CFTR

Research Areas:  

Inflammation/Immunology

CFTR corrector 13 (SVQ18) is a cystic fibrosis transmembrane conductance regulator (CFTR) corrector (EC50=3.14 μM). CFTR corrector 13 enhances the function of CFTR channels, especially when used in combination with Lumacaftor (HY-13262), it can produce a dose-dependent increase in CFTR function. CFTR corrector 13 can be used in the study of cystic fibrosis (CF) and other CFTR-related diseases .
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