53 Results for "

MRSA strain

" in MedChemExpress (MCE) Product Catalog:
Products (53)

53 Results for "MRSA strain" in MCE Product Catalog:

66
66 Publications Verification
Cat. No.: HY-13067
CAS No.: 34157-83-0
Purity:  99.64%
Synonyms: Tripterine; Tripterin
Celastrol (Tripterine;Tripterin) is a proteasome inhibitor which potently and preferentially inhibits the chymotrypsin-like activity of a purified 20S proteasome with IC50 of 2.5 μM. In addition, Celastrol is also an antibiotic with potent antimicrobial activity against standard and clinical methicillin-resistant Staphylococcus aureus (MRSA) strains, inducing oxidative stress and inhibiting DNA synthesis by binding to P5CDH .
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3
3 Cited Publications
Cat. No.: HY-B2234
CAS No.: 25655-41-8
Synonyms: iodopovidone
Research Areas:  

Infection

Povidone iodine (iodopovidone) displays excellent antibacterial activity which can against MRSA and MSSA strains with MICs of 31.25 mg/L and 7.82 mg/L, respectively.
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1
1 Cited Publications
Cat. No.: HY-16485
CAS No.: 560130-42-9
Synonyms: TD-6424 hydrochloride
Target:  

Antibiotic Bacterial

Research Areas:  

Infection

Telavancin hydrochloride is the hydrochloride form of Telavancin (HY-112959). Telavancin hydrochloride is a semisynthetic derivative of vancomycin, and exhibits antibacterial efficacy through inhibition of cell wall synthesis and disruption of cell membrane barrier function. Telavancin hydrochloride is efficient against antibiotic resistant S. aureus strains MRSA, VISA, and hVISA. Telavancin hydrochloride attenuates gram positive bacteria induced complicated skin and skin structure infections (cSSSI) .
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Cat. No.: HY-133119
CAS No.: 2165324-62-7
Purity:  99.43%
Target:  

Bacterial

Research Areas:  

Infection

PK150, an analogue of Sorafenib, shows oral bioavailability and antibacterial activity against several pathogenic strains at submicromolar concentrations. PK150 inhibits Gram-positive Methicillin-sensitive S. aureus (MSSA), Methicillin-resistant S. aureus (MRSA), Vancomycin intermediate S. aureus (VISA) with MICs of 0.3, 0.3-1, 0.3 μM, respectively .
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Cat. No.: HY-Y0191
CAS No.: 142-08-5
Synonyms: 2-Pyridone
α-Pyridone (2-Pyridone) is an antibacterial agent that plays an important role in the field of biochemical research. α-Pyridone can serve as a scaffold compound to synthesize a variety of active compounds .
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Cat. No.: HY-14926
CAS No.: 154357-42-3
Purity:  99.79%
Synonyms: (S)-(-)-Nadifloxacin; WCK 771
Target:  

Antibiotic Bacterial

Research Areas:  

Infection

Levonadifloxacin ((S)-(-)-Nadifloxacin; WCK 771) is a broad-spectrum anti-staphylococcal agent. Levonadifloxacin shows antibacterial activity against Methicillin (HY-121544)-susceptible Staphylococcus aureus (MSSA) and Methicillin-resistant S. aureus (MRSA) strains, with a reduction of which phagocytized in THP-1 monocytes .
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Cat. No.: HY-N15451
CAS No.: 112515-42-1
Deoxytopsentin (compound 5) is a marine bisindole alkaloid and also a MRSA pyruvate kinase inhibitor. Deoxytopsentin exists in sponges. Deoxytopsentin exhibits antibacterial activity against methicillin-resistant Staphylococcus aureus strains in vitro .
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Cat. No.: HY-N3920
CAS No.: 126716-34-5
Gancaonin G is a 6-prenylated isoflavanone that can be isolated from Glycyrrhiza uralensis. Gancaonin G has antibacterial activity against Streptococcus mutants and MRSA strains .
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Cat. No.: HY-121300
CAS No.: 183202-73-5
Purity:  98.00%
Synonyms: (-)-TAN2162
Kendomycin ((−)-TAN 2162) is a polyketide antibiotic with remarkable antibacterial and cancer cells cytotoxic activities. Kendomycin tends to be bacteriostatic rather than bactericidal and inhibits the growth of the methicillin-resistant Staphylococcus aureus (MRSA) strain COL at a low concentration (MIC of 5 μg/mL). Kendomycin is a potent antagonist of the endothelin receptor and a calcitonin receptor agonist which plays its role as an anti-osteoporotic agent .
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Cat. No.: HY-P5710
CAS No.: 343593-45-3
Target:  

Bacterial

Research Areas:  

Infection

LCI peptide is an antimicrobial peptide with antibacterial activity. LCI peptide is active against plant pathogens, Xanthomonas and Pseudomonas, including E. coli, Gentamicin-resistant MRSA and Xoo .
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Cat. No.: HY-P5545
Target:  

Bacterial

Research Areas:  

Infection

Lynronne-1 is an antimicrobial peptide. Lynronne-1 is active against Gram-positive bacterials, including MDR strains (MIC: 8-32 μg/mL for methicillin-resistant MRSA strains). Lynronne-1 reduces the bacterial load in MRSA infected wound murine model. Lynronne-1 is also effective against P. aeruginosa infection .
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Cat. No.: HY-129487
CAS No.: 219140-31-5
Target:  

Bacterial

Research Areas:  

Infection

(E/Z)-MC4 is an enantiomer of the antibacterial agent MC4, which has antibacterial activity against a group of Staphylococcus aureus strains including MRSA, and has no significant toxicity to mammalian cells .
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Cat. No.: HY-130613
CAS No.: 838810-96-1
Purity:  98.01%
Target:  

Bacterial

Research Areas:  

Infection

MAC-545496 is a nanomolar inhibitor of glycopeptide-resistance-associated protein R (GraR). MAC-545496 displays strong binding affinity to the full-length GraR protein (Kd ≤ 0.1 nM). MAC-545496 is an antivirulence agent that reverses β-lactam resistance in Methicillin-resistant strains (MRSA) .
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Cat. No.: HY-B1606
CAS No.: 89-68-9
Synonyms: Chlorthymol; 6-Chlorothymol
Chlothymol is a potent positive modulator of the GABAA receptor subunit LGC-37, anticonvulsant, and antibacterial agent. Chlothymol inhibits Pentylenetetrazol-induced c-fos expression. Chlothymol inhibits the growth of Methicillin (HY-121544)-resistant Staphylococcus aureus (MRSA) strains, including LAC, with an MIC of 32 μg/mL. Chlorothymol has protective effects against epileptic seizures in various mouse models .
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Cat. No.: HY-W060074
CAS No.: 50892-83-6
1-Acetyl-β-carboline is a metabolite of Streptomyces kasugaensis and antibacterial agent. 1-Acetyl-β-carboline increases tyrosinase activity, reduces ERK phosphorylation. 1-Acetyl-β-carboline exhibits antibacterial activity against methicillin-resistant Staphylococcus aureus (MRSA) strains with MICs ranging from 128 to 256 ug/mL. 1-Acetyl-β-carboline increases the melanin .
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Cat. No.: HY-P5706
Target:  

Bacterial

Research Areas:  

Infection Inflammation/Immunology

HG2 is a fast-acting antimicrobial peptide. HG2 shows anti-biofilm and anti-inflammatory activities. HG2 is active against Gram-positive pathogens, especially against MRSA strains (MIC: 16-32 μg/mL). HG2 can bind to bacterial lipids and reduces ATP concentration in S. aureus MRSA USA300 cells .
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Cat. No.: HY-178949
Research Areas:  

Infection

MRSA antibiotic 3 (Compound C8) is a small-molecule antibiotic active against Methicillin (HY-121544)-resistant Staphylococcus aureus (MRSA), showing a MIC of 0.5 μg/mL against the standard S. aureus strain (ATCC 29213). MRSA antibiotic 3 potently inhibits the ATPase activity of S. aureus DNA gyrase with an IC50 of 0.32 μM. MRSA antibiotic 3 exhibits strong inhibitory activity against five clinical MRSA isolates, with MIC values ranging from 0.5 to 1 μg/mL. MRSA antibiotic 3 demonstrates negligible cytotoxicity at effective antibacterial concentrations and causes no hemolysis in erythrocytes even at extremely high concentrations. MRSA antibiotic 3 shows significant protective effects in both Galleria mellonella infection and murine sepsis models .
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Cat. No.: HY-P5547
Target:  

Bacterial

Research Areas:  

Infection

Lynronne-3 is an antimicrobial peptide. Lynronne-1 is active against Gram-positive bacterials, including MDR strains (MIC: 32-128 μg/mL for methicillin-resistant MRSA strains). Lynronne-3 is also effective against P. aeruginosa infection
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Cat. No.: HY-P10345
CAS No.: 732984-81-5
Target:  

Bacterial

Research Areas:  

Infection

OP-145, an cathelicidin LL-37 derivative, is an antimicrobial peptide, and shows antibacterial activity against several MRSA strains. OP-145 can be used for research of chronic suppurative otitis media .
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Cat. No.: HY-126183
CAS No.: 151649-32-0
6,8-Diprenyleriodictyol is a flavonoid and bactericidal agent. 6,8-Diprenyleriodictyol can be isolated from the aerial parts of D. mannii. 6,8-Diprenyleriodictyol shows significant antibacterial activity against S. aureus including MRSA strains .
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