50892-83-6
Chemical Structure
1-Acetyl-β-carboline
- CAS No.: 50892-83-6
- Formula:C13H10N2O
- Molecular Weight:210.23
IUPAC Name: 1-(9H-pyrido[3,4-b]indol-1-yl)ethan-1-one
InChIKey: NXZSUJKPVSDFNF-UHFFFAOYSA-N
SMILES: CC(C1=NC=CC2=C1NC3=CC=CC=C32)=O
Biological Activity: 1-Acetyl-β-carboline is a metabolite of Streptomyces kasugaensis and antibacterial agent. 1-Acetyl-β-carboline increases tyrosinase activity, reduces ERK phosphorylation. 1-Acetyl-β-carboline exhibits antibacterial activity against methicillin-resistant Staphylococcus aureus (MRSA) strains with MICs ranging from 128 to 256 ug/mL. 1-Acetyl-β-carboline increases the melanin[1][2][3].
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1-Acetyl-β-carboline | 97.04% | 1-Acetyl-β-carboline is a metabolite of Streptomyces kasugaensis and antibacterial agent. 1-Acetyl-β-carboline increases tyrosinase activity, reduces ERK phosphorylation. 1-Acetyl-β-carboline exhibits antibacterial activity against methicillin-resistant Staphylococcus aureus (MRSA) strains with MICs ranging from 128 to 256 ug/mL. 1-Acetyl-β-carboline increases the melanin. | ||||||||||||||||||||
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- [1]. PROKSA B, et al. 1-Acetyl-β-carboline, a new metabolite of Streptomyces kasugaensis. Acta Biotechnologica (Acta Biotechnol). Volume： 10 Issue： 4 Page： 337-340 Publication year： 1990.
- [2]. Shin H J, et al. The Synergistic Antibacterial Activity of 1-Acetyl--Carboline and -Lactams Against Methicillin-Resistant Staphylococcus aureus (MRSA). Journal of microbiology and biotechnology, 2010, 20(3): 501-505.
- [3]. Hyun KA, et al. 1-Acetyl-β-Carboline from a Jeju Gotjawal Strain Lentzea sp. JNUCC 0626 and Its Melanogenic Stimulating Activity in B16F10 Melanoma Cells. Molecules. 2024 Sep 27;29(19):4586. [Content Brief]
Keywords
