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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
12 Results for "
Monopolar spindle 1
" in MedChemExpress (MCE) Product Catalog:
Products (12)
12 Results for "Monopolar spindle 1" in MCE Product Catalog:
9
9 Cited Publications
BAY 1217389 is a potent, and selective inhibitor of the monopolar spindle 1 (MPS1) kinase with an IC50 value less than 10 nM.
2
2 Cited Publications
BOS-172722 is an inhibitor of monopolar spindle 1 (MPS1) checkpoint with an IC50 of 11 nM and 63 nM for MPS1 (1 mM ATP) and P-MPS1, respectively. BOS-172722 also has potential for the study of various forms of breast cancer .
TC-Mps1-12 is a potent and selective monopolar spindle 1 (Mps1) inhibitor, with an IC50 of 6.4 nM .
Cat. No.: HY-168540
Research Areas:
PROTAC MPS1 degrader 1 is a selective monopolar spindle 1 (Mps1/TTK) PROTAC degrader, with DC50 values of 17.7, 108.67 and 570.25 nM against TTK, AURKA and AURKB, respectively. PROTAC MPS1 degrader 1 exhibits cytotoxicity against acute myeloid leukemia cells. PROTAC MPS1 degrader 1 can be used in research related to acute myeloid leukemia .
Cat. No.: HY-168542
Research Areas:
TTK ligand 2 is a monopolar spindle 1 (TTK) ligand that can be used in the synthesis of PROTACT (HY-168540) .
Cat. No.: HY-101071
CAS No.: 254753-54-3
Synonyms: (+)-Monastrol
(S)-Monastrol ((+)-Monastrol) is an allosteric inhibitor of the mitotic kinesin Eg5 that exhibits an antiproliferative effect against several cancer cell lines. (S)-Monastrol arrests mammalian cells in mitosis with monopolar spindles .
Cat. No.: HY-P701653
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: TTK; MPS1; MPS1L1; Dual specificity protein kinase TTK; EC 2.7.12.1; Phosphotyrosine picked threonine-protein kinase; PYT; ESK; Monopolar spindle 1-Like 1; Cancer/Testis Antigen 96; Monopolar spindle 1 Kinase; Threonine And Tyrosine Kinase; Phosphotyrosin
Species:
Human
Source:
Sf9 insect cells
Cat. No.: HY-110242R
CAS No.: 1382477-96-4
Target:
Research Areas:
Mps-BAY2a (Standard) is the analytical standard of Mps-BAY2a (HY-110242). This product is intended for research and analytical applications. Mps-BAY2a is a monopolar spindle 1 (MPS1) inhibitor with an IC50 of 1 nM against human MPS1. Mps-BAY2a induces mitotic aberrations and apoptosis in cancer cells .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
