1. Cell Cycle/DNA Damage
    Cytoskeleton
  2. Mps1

BOS-172722 

Cat. No.: HY-112162 Purity: 99.41%
Handling Instructions

BOS-172722 is an inhibitor of monopolar spindle 1 (MPS1) checkpoint with an IC50 of 2 nM.

For research use only. We do not sell to patients.

BOS-172722 Chemical Structure

BOS-172722 Chemical Structure

CAS No. : 1578245-44-9

Size Price Stock Quantity
10 mM * 1 mL in DMSO USD 580 In-stock
Estimated Time of Arrival: December 31
1 mg USD 190 In-stock
Estimated Time of Arrival: December 31
5 mg USD 590 In-stock
Estimated Time of Arrival: December 31
10 mg USD 890 In-stock
Estimated Time of Arrival: December 31
25 mg USD 1750 In-stock
Estimated Time of Arrival: December 31
50 mg USD 2450 In-stock
Estimated Time of Arrival: December 31
100 mg USD 3850 In-stock
Estimated Time of Arrival: December 31
200 mg   Get quote  
500 mg   Get quote  

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Description

BOS-172722 is an inhibitor of monopolar spindle 1 (MPS1) checkpoint with an IC50 of 2 nM.

IC50 & Target

2 nM (MPS1)[1].

In Vitro

BOS-172722 is an inhibitor of monopolar spindle 1 (MPS1) checkpoint with an IC50 of 2 nM. BOS-172722 also has potential for the treatment of various forms of breast cancer[1].

Clinical Trial
Solvent & Solubility
In Vitro: 

DMSO : < 1 mg/mL (insoluble or slightly soluble)

H2O : < 0.1 mg/mL (insoluble)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.2394 mL 11.1970 mL 22.3939 mL
5 mM 0.4479 mL 2.2394 mL 4.4788 mL
10 mM 0.2239 mL 1.1197 mL 2.2394 mL
*Please refer to the solubility information to select the appropriate solvent.
References
Molecular Weight

446.55

Formula

C₂₄H₃₀N₈O

CAS No.

1578245-44-9

SMILES

CC1=CC2=CN=C(NC3=CC=C(C4=NN=CN4C)C=C3OCC)N=C2C(NCC(C)(C)C)=N1

Storage
Powder -20°C 3 years
  4°C 2 years
In solvent -80°C 6 months
  -20°C 1 month
Shipping

Room temperature in continental US; may vary elsewhere

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Product Name:
BOS-172722
Cat. No.:
HY-112162
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BOS-172722

Cat. No.: HY-112162