3 Results for "

NMDAR modulator1

" in MedChemExpress (MCE) Product Catalog:
Products (3)

3 Results for "NMDAR modulator1" in MCE Product Catalog:

1
1 Cited Publications
Cat. No.: HY-16940
CAS No.: 474-73-7
Synonyms: 24S-OHC; 24S-HC; Cerebrosterol
24(S)-Hydroxycholesterol (24S-OHC), the major brain cholesterol metabolite, plays an important role to maintain homeostasis of cholesterol in the brain. 24(S)-Hydroxycholesterol (24S-OHC) is one of the most efficient endogenous LXR agonist known and is present in the brain and in the circulation at relatively high levels. 24(S)-Hydroxycholesterol (24S-OHC) is a very potent, direct, and selective positive allosteric modulator of NMDARs with a mechanism that does not overlapthat of other allosteric modulators .
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Cat. No.: HY-179108
Target:  

iGluR

Research Areas:  

Neurological Disease

NMDAR modulator 1 (Compound 12) is a positive, allosteric GluN1/GluN2B receptor modulator. NMDAR modulator 1 enhances NMDAR current. NMDAR modulator 1 can be used in the research of psychiatric disorders .
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Cat. No.: HY-181127
CAS No.: 2419700-58-4
Target:  

iGluR

Research Areas:  

Neurological Disease

GluN2B-NMDAR Allosteric modulator 1 is a selective GluN2B-NMDAR positive allosteric modulator. GluN2B-NMDAR Allosteric modulator 1 can increase glutamate- and aspartate-evoked GluN2B-NMDAR-gated currents with EC50 values of 43.7 and 18 nM. GluN2B-NMDAR Allosteric modulator 1 can reverse anxiety-like behavior and social cognition deficits in mice. GluN2B-NMDAR Allosteric modulator 1 can be used for the research of neurological disease, such as anxiety .
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