55 Results for "

NS-1

" in MedChemExpress (MCE) Product Catalog:
Products (55)

55 Results for "NS-1" in MCE Product Catalog:

1
1 Cited Publications
Cat. No.: HY-P700618
Purity:  ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: PTPN11; Protein Tyrosine Phosphatase Non-Receptor Type 11 Isoform 1; Prev. NS1; Tyrosine-Protein Phosphatase Non-Receptor Type; SH-PTP2; Protein-Tyrosine-Phosphatase; PTP2C; Noonan Syndrome 1; BPTP3; CDNA, FLJ92431; SHP-2; PTPN11 Protein; SHP2; METCDS; SH
Species:  
Source:  
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Cat. No.: HY-P0221C
CAS No.: 129405-61-4
Target:  

PACAP Receptor

Research Areas:  

Metabolic Disease

PACAP (1-38) free acid is a desamido-PACAP (1-38), human, ovine, rat (HY-P0221). PACAP (1-38) free acid can activate the human PAC1 receptor. PACAP (1-38) free acid induces cyclic AMP (cAMP) generation in both NS-1 neuroendocrine cells and non-neuroendocrine HEK293 cells [1].
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Cat. No.: HY-P10927A
Synonyms: BRINP2-related peptide TFA
Target:  

PKA AP-1

Research Areas:  

Metabolic Disease

BRP (BRINP2-related peptide) TFA is a 12-peptide derived from BRINP2 that can cross the blood-brain barrier. BRP TFA induces the central activation of FOS in neuronal cells via the cAMP-PKA-CREB signaling pathway. BRP TFA exerts anorectic and anti-obesity effects without triggering nausea or aversive responses. The action of BRP TFA is independent of the leptin, GLP-1 receptor and melanocortin 4 receptor pathways. BRP TFA is applicable to obesity-related research [1].
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Cat. No.: HY-P10927
Synonyms: BRINP2-related peptide
Target:  

AP-1 PKA

Research Areas:  

Metabolic Disease

BRP is a 12-peptide derived from BRINP2 that can cross the blood-brain barrier. BRP induces the central activation of FOS in neuronal cells via the cAMP-PKA-CREB signaling pathway. BRP exerts anorectic and anti-obesity effects without triggering nausea or aversive responses. The action of BRP is independent of the leptin, GLP-1 receptor and melanocortin 4 receptor pathways. BRP is applicable to obesity-related research [1].
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Cat. No.: HY-126136
CAS No.: 1638211-04-7
Purity:  99.62%
Target:  

Influenza Virus

Research Areas:  

Infection

ML303 is a pyrazolopyridine influenza virus nonstructural protein 1 (NS1) antagonist (IC90 = 155 nM), with an EC50 of 0.7 μM for Influenza A virus H1N1 [1].
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Cat. No.: HY-134922
CAS No.: 181373-35-3
Synonyms: REDD1 inducer-1
Target:  

Influenza Virus mTOR

Research Areas:  

Infection

NS1-IN-1 (REDD1 inducer-1) is a naphthalimide compound and an NS1 inhibitor. NS1-IN-1 antagonizes influenza A virus NS1-mediated inhibition of host gene expression and induces REDD1 expression. NS1-IN-1 suppresses the mTORC1 signaling pathway via a TSC1-TSC2 dependent mechanism. NS1-IN-1 exhibits broad antiviral activity against influenza virus and vesicular stomatitis virus (VSV), with low toxicity [1].
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Cat. No.: HY-N16392
CAS No.: 3085255-21-3
14-epi-Berkeleylactone F (Compound 8) is a C-14 epimer of Berkeleylactone F (HY-N8386). 14-epi-Berkeleylactone F can be isolated from Penicillium turbatum NRRL 5630. 14-epi-Berkeleylactone F has no significant biological activity against bacterium (Staphylococcus aureus, Bacillus subtilis and E. coli), fungi Candida albicans, the parasite Giardia duodenalis and NS-1 murine myeloma cells [1].
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Cat. No.: HY-118565
CAS No.: 18463-11-1
Rhizocarpic acid (Compound 2) is a secondary metabolite of lichen. Rhizocarpic acid effectively inhibits the growth of bacteria, such as Bacillus subtilis and Staphylococcus aureus, as well as murine myeloma NS-1 cells. Rhizocarpic acid is an antioxidant and an insect antifeedant with an ED50 of 71 μmol/g dry weight against neonate larvae of the Egyptian cotton leaf worm Spodoptera littoralis [1] .
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Cat. No.: HY-N15480
Nanangenine C is a drimane sesquiterpene that has been found in Aspergillus. It is active against B. subtilis (IC50 = 5.7 μg/ml) and cytotoxic to NS-1 mouse myeloma cells (IC50 = 4.1 μg/ml).
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Cat. No.: HY-118427
CAS No.: 287117-66-2
Asterriquinol D dimethyl ether is a fungal metabolite, which can inhibit mouse myeloma NS-1 cell lines with an IC50 of 28 μg/mL. Asterriquinol D dimethyl ether also inhibits Tritrichomonas foetus [1].
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Cat. No.: HY-N11989
CAS No.: 1609469-72-8
Target:  

Others

Nanangenine B is a sesquiterpenoid, which can be isolated from Aspergillus nanangensis. Nanangenine B exhibits cytotixicity in cancer cell NS-1 with an IC50 of 38 μg/mL [1].
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Cat. No.: HY-P991774

Target:  

Flavivirus

Research Areas:  

Infection

Anti-West Nile virus NS1 Antibody (10NS1) reacts with non-structural protein 1 (NS1) of West Nile virus (WNV). Anti-West Nile virus NS1 Antibody (10NS1) offers significant protection against flaviviral infections in vivo. Recommend Isotype Controls: Mouse IgG2a kappa, Isotype Control (HY-P99978) [1].
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Cat. No.: HY-177540
CAS No.: 3061155-24-3
Research Areas:  

Infection Cancer

ent-Rhizocarpic acid is an enantiomer of Rhizocarpic acid. ent-Rhizocarpic acid has more potent antibacterial and antiparasitic activity against Staphylococcus aureus (ATCC 25923) and Giardiaduodenalis 713 compared to Rhizocarpic acid. ent-Rhizocarpic acid also has a weak but selective antitumor activity against NS-1 cells [1].
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Cat. No.: HY-N12264
CAS No.: 2334483-46-2
Burnettramic acid A is an antibiotic, which can be isolated from Aspergillus burnettii. Burnettramic acid A exhibits antibacterial and antifungal activities, with IC50 of 0.2, 0.5, 2.3 and 5.9 μg/mL, for Saccharomyces cerevisiae, Candida albicans, Bacillus subtilis and Staphylococcus aureus, respectively. Burnettramic acid A exhibits cytotoxicity in cancer cell NS-1 with IC50 of 13.8 μg/mL [1].
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Cat. No.: HY-177815
Target:  

Influenza Virus

Research Areas:  

Infection

R-1 sodium is a RNA aptamer that bind to Non-structural protein 1 (NS1) (Kd = 1.62 ± 0.30 nM). R-1 sodium inhibits the interaction of NS1 with tripartite motif-containing protein 25 (TRIM25), and suppression of NS1 enabled retinoic acid inducible gene I (
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Cat. No.: HY-177816
Target:  

Influenza Virus

Research Areas:  

Infection

R-2 sodium is a RNA aptamer that bind to Non-structural protein 1 (NS1) (Kd = 1.92 ± 0.27 nM). R-2 sodium inhibits the interaction of NS1 with tripartite motif-containing protein 25 (TRIM25), and suppression of NS1 enabled retinoic acid inducible gene I (
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Cat. No.: HY-125092
CAS No.: 204398-92-5
Target:  

Antibiotic

Research Areas:  

Infection

Drimentine C is a terpenylated diketopiperazine antibiotic originally isolated from Actinomycete bacteria. It inhibits proliferation of NS-1 murine β lymphocyte myeloma cells by 63 and 98% in vitro when used at concentrations of 12.5 and 100 μg/mL, respectively.
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Cat. No.: HY-118079
CAS No.: 204398-91-4
Target:  

Endogenous Metabolite

Research Areas:  

Infection

Drimentine B is a terpenylated diketopiperazine originally isolated from Actinomycete bacteria that has anticancer activity. It inhibits the proliferation of NS-1 murine β lymphocyte myeloma cells by 41 and 59% in vitro when used at concentrations of 50 and 100 μg/mL, respectively.
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Cat. No.: HY-N10259
CAS No.: 581786-63-2
Norfunalenone exhibits weak cytotoxic activity in mouse myeloma NS-1 cell line (ATCC TIB-18) with an IC50 of 70 μM. Norfunalenone also exhibits weak antibacterial activity against B. subtilis (MIC=100 μg/mL; IC50=265 μM) [1].
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Cat. No.: HY-RS07001
Research Areas:  

Others

IVNS1ABP Human Pre-designed siRNA Set A contains three designed siRNAs for IVNS1ABP gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

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