Nanangenine B
Nanangenine B is a sesquiterpenoid, which can be isolated from Aspergillus nanangensis. Nanangenine B exhibits cytotixicity in cancer cell NS-1 with an IC50 of 38 μg/mL.
For research use only. We do not sell to patients.
- CAS No.: 1609469-72-8
- Formula: C21H32O6
- Molecular Weight:380.48
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| DLD-1 | IC50 |
49 μM
Compound: 2
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Inhibition of TNF-alpha/IFN-gamma/IL-1beta-induced human CXCL10 (972 bp) promoter activity expressed in human DLD1 cells after 24 hrs by IRSE-driven luciferase reporter assay
Inhibition of TNF-alpha/IFN-gamma/IL-1beta-induced human CXCL10 (972 bp) promoter activity expressed in human DLD1 cells after 24 hrs by IRSE-driven luciferase reporter assay
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[PMID: 24792812] |
| DLD-1 | IC50 |
50.7 μM
Compound: 2
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Inhibition of Stat1 (unknown origin)-induced human CXCL10 (972 bp) promoter activity expressed in TNF-alpha/IFN-gamma/IL-1beta-stimulated human DLD1 cells after 24 hrs by luciferase reporter assay
Inhibition of Stat1 (unknown origin)-induced human CXCL10 (972 bp) promoter activity expressed in TNF-alpha/IFN-gamma/IL-1beta-stimulated human DLD1 cells after 24 hrs by luciferase reporter assay
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[PMID: 24792812] |
| DLD-1 | IC50 |
55 μM
Compound: 2
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Inhibition of TNF-alpha/IFN-gamma/IL-1beta-induced human CXCL10 (972 bp) promoter activity expressed in human DLD1 cells after 24 hrs by luciferase reporter assay
Inhibition of TNF-alpha/IFN-gamma/IL-1beta-induced human CXCL10 (972 bp) promoter activity expressed in human DLD1 cells after 24 hrs by luciferase reporter assay
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[PMID: 24792812] |
| DLD-1 | IC50 |
68.4 μM
Compound: 2
|
Inhibition of NF-kappaB (unknown origin)-induced human CXCL10 (972 bp) promoter activity expressed in TNF-alpha/IFN-gamma/IL-1beta-stimulated human DLD1 cells after 24 hrs by luciferase reporter assay
Inhibition of NF-kappaB (unknown origin)-induced human CXCL10 (972 bp) promoter activity expressed in TNF-alpha/IFN-gamma/IL-1beta-stimulated human DLD1 cells after 24 hrs by luciferase reporter assay
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[PMID: 24792812] |
Chemical Information
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CAS No. 1609469-72-8
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Molecular Weight 380.48
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Formula C21H32O6
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SMILES
C[C@]12[C@@](C(C)(CC[C@H]2O)C)([H])[C@@H](C=C3[C@@]1(C(OC3)=O)O)OC(CCCCC)=O
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Structure Classification
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Initial Source
Aspergillus
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Nanangenine B Related Classifications
HY-N11989 Related Classifications
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