Asterriquinol D dimethyl ether
Asterriquinol D dimethyl ether is a fungal metabolite, which can inhibit mouse myeloma NS-1 cell lines with an IC50 of 28 μg/mL. Asterriquinol D dimethyl ether also inhibits Tritrichomonas foetus.
For research use only. We do not sell to patients.
- CAS No.: 287117-66-2
- Formula: C26H24N2O4
- Molecular Weight:428.48
-
Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
Description
IC50 & Target
|
Microbial Metabolite |
Cellular Effect
|
Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| L02 | IC50 |
>100 μM
Compound: 2
|
Cytotoxicity against human L02 cells assessed as cell growth inhibition incubated for 72 hrs by Cell Titer-Glo assay
Cytotoxicity against human L02 cells assessed as cell growth inhibition incubated for 72 hrs by Cell Titer-Glo assay
|
[PMID: 37857311] |
| MV4-11 | IC50 |
5.9 μM
Compound: 2
|
Cytotoxicity against human MV4-11 cells assessed as cell growth inhibition incubated for 72 hrs by Cell Titer-Glo assay
Cytotoxicity against human MV4-11 cells assessed as cell growth inhibition incubated for 72 hrs by Cell Titer-Glo assay
|
[PMID: 37857311] |
Chemical Information
-
CAS No. 287117-66-2
-
Molecular Weight 428.48
-
Formula C26H24N2O4
-
SMILES
COC1=C(C(OC)=C(C(C2=CNC3=C2C=CC=C3)=C1OC)OC)C4=CNC5=C4C=CC=C5
-
Structure Classification
-
Initial Source
Aspergillus kumbius
-
Shipping
Room temperature in continental US; may vary elsewhere.
-
Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Protocols
-
Cell Cytotoxicity Assay
Cytotoxicity assays are usually based on the assessment of cell membrane damage, which can also be indirectly detected by measuring cell viability. Detection methods include MTT assay, CKK-8 assay, LDH assay and ATP assay, etc.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)