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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
32 Results for "
Niacin
" in MedChemExpress (MCE) Product Catalog:
Products (32)
32 Results for "Niacin" in MCE Product Catalog:
12
97
97 Publications Verification
Synonyms: Niacinamide; Nicotinic acid amide
28
28 Cited Publications
Category:
Alkaloids Neurological Disease Animals Anti-aging Pyridine Alkaloids Metabolic Disease Disease Research Fields
Target:
28
28 Cited Publications
Category:
Natural Products Neurological Disease Metabolic Disease Endogenous metabolite Disease Research Fields
Target:
28
28 Cited Publications
Cat. No.: HY-123033B
CAS No.: 2415657-86-0
Category:
Natural Products Neurological Disease Metabolic Disease Endogenous metabolite Disease Research Fields
Target:
12
12 Cited Publications
Synonyms: Nicotinic acid hydrochloride; Vitamin B3 hydrochloride
Category:
Alkaloids Ketones, Aldehydes, Acids Pyridine Alkaloids Metabolic Disease Endogenous metabolite Disease Research Fields Cancer
Target:
1
1 Cited Publications
Synonyms: Niacinamide(Standard); Nicotinic acid amide (Standard)
Research Areas:
Nicotinamide (Standard) is the analytical standard of Nicotinamide. This product is intended for research and analytical applications. Nicotinamide is a form of vitamin B3 or niacin. Nicotinamide Hydrochloride inhibits SIRT2 activity (IC50: 2 μM). Nicotinamide also inhibits SIRT1. Nicotinamide increases cellular NAD+, ATP, ROS levels. Nicotinamide inhibits tumor growth and improves survival. Nicotinamide also has anti-HBV activity .
1
1 Cited Publications
Cat. No.: HY-B0143S2
CAS No.: 66148-15-0
Synonyms: Nicotinic acid-d4; Vitamin B3-d4
1
Target:
1
1 Cited Publications
Research Areas:
LUF6283 is a potent and orally active HCA(2) partial agonist, with a Ki of 0.55 µM. LUF6283 can achieve the beneficial lipid lowering effect of niacin without producing the unwanted cutaneous flushing side effect .
Category:
Human Gut Microbiota Metabolites Natural Products Microorganisms Neurological Disease Animals Anti-aging Metabolic Disease Endogenous metabolite Disease Research Fields
Target:
Target:
Research Areas:
Cardiovascular Disease Metabolic Disease Inflammation/Immunology
GPR109 receptor agonist-1 is a highly selective agonist of the human orphan G protein-coupled receptor GPR109b, and does not activate the mouse homologous receptor PUMA-G. GPR109 receptor agonist-1 functionally modulates the human GPR109b receptor via the cAMP signaling pathway, with an EC50 of 400 nM. GPR109 receptor agonist-1 inhibits isoproterenol (HY-B0468)-stimulated lipolysis in human subcutaneous adipocytes, with efficacy comparable to that of Niacin (HY-B0143), and does not act on β-adrenergic receptors. GPR109 receptor agonist-1 can be used in studies related to dyslipidemia and atherosclerosis .
Cat. No.: HY-B0757A
CAS No.: 51898-34-1
Synonyms: rel-Vitamin E Nicotinate
Category:
Alkaloids Microorganisms Ketones, Aldehydes, Acids Disease markers Nervous System Disorder Endogenous metabolite
Target:
Cat. No.: HY-123033AR
CAS No.: 23111-00-4
Category:
Cat. No.: HY-B0143S3
CAS No.: 1189954-79-7
Synonyms: Nicotinic acid-13C6; Vitamin B3-13C6
Cat. No.: HY-W004580
CAS No.: 1802-30-8
Target:
Research Areas:
5,5'-Dicarboxy-2,2'-bipyridine is a niacin derivative, which is promising for research of hypercholesterolemia, hyperlipidemia, and cardiovascular disease .
Cat. No.: HY-W002864
CAS No.: 6311-35-9
Cat. No.: HY-W015793
CAS No.: 3167-49-5
Research Areas:
6-Aminonicotinic acid is an analog of Niacin (HY-B0143) and also a GABAA receptor agonist with a Ki value of 4.4 μM in rats. 6-Aminonicotinic acid binds to both native and recombinant GABAA receptors, is metabolized into non-functional pyridine nucleotide analogs to inhibit dehydrogenases, and suppresses the proliferation of T2 bacteriophages. 6-Aminonicotinic acid accumulates in specific bacterial cells in the form of pyridine nucleotide analog metabolites. 6-Aminonicotinic acid can be used in research related to neurological disorders such as anxiety, epilepsy and schizophrenia, and also serves as an intermediate in organic synthesis .
Cat. No.: HY-17640
CAS No.: 1269181-69-2
Target:
Research Areas:
Nicodicosapent is a fatty acid niacin conjugate that is also an inhibitor of the sterol regulatory element binding protein (SREBP), a key regulator of cholesterol metabolism proteins such as PCSK9, HMG-CoA reductase, ATP citrate lyase, and NPC1L1.
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
