72420-38-3
72420-38-3
Chemical Structure
Acifran
Synonym(s): AY 25712
- CAS No.: 72420-38-3
- Formula:C12H10O4
- Molecular Weight:218.21
IUPAC Name: 5-methyl-4-oxo-5-phenyl-4,5-dihydrofuran-2-carboxylic acid
InChIKey: DFDGRKNOFOJBAJ-UHFFFAOYSA-N
SMILES: O=C(C(OC1(C)C2=CC=CC=C2)=CC1=O)O
Biological Activity: Acifran (AY 25712), an antihyperlipidemic agent, is an orally active agonist of GPR109A (HM74A) and GPR109B, the high and low affinity receptors for Niacin[1][2].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Acifran | 99.03% | Acifran (AY 25712), an antihyperlipidemic agent, is an orally active agonist of GPR109A (HM74A) and GPR109B, the high and low affinity receptors for Niacin. | ||||||||||||||||||||
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Acifran (Standard) | ≥98% | (2S,5R,6R)-Ticarcillin (disodium) (Standard) is the analytical standard of (2S,5R,6R)-Ticarcillin (disodium). This product is intended for research and analytical applications. (2S,5R,6R)-Ticarcillin disodium is an injectable antibiotic for the treatment of Gram-negative bacteria, particularly Pseudomonas aeruginosa. It is also one of the few antibiotics capable of treating Stenotrophomonas maltophilia infections. | ||||||||||||||||||||
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References
- [1]. M N Cayen, et al. The metabolic disposition of acifran, a new antihyperlipidemic agent, in rats and dogs. Xenobiotica. 1986 Mar;16(3):251-63. [Content Brief]
- [2]. Jae-Kyu Jung, et al. Analogues of acifran: agonists of the high and low affinity niacin receptors, GPR109a and GPR109b. J Med Chem. 2007 Apr 5;50(7):1445-8. [Content Brief]
Keywords
