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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
21 Results for "
Nifedipine
" in MedChemExpress (MCE) Product Catalog:
Products (21)
21 Results for "Nifedipine" in MCE Product Catalog:
29
Target:
Research Areas:
Nifedipine (BAY-a-1040) is a potent calcium channel blocker and agent of choice for cardiac insufficiencies.
4
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Nitrendipine (BAY-E-5009) is an orally active analog of Nifedipine (HY-B0284) and dihydropyridine calcium channel blocker. Nitrendipine induces Apoptosis. Nitrendipine has antihypertensive effects. Nitrendipine blocks alcohol and Morphine withdrawal symptoms. Nitrendipine reduces right ventricular hypertrophy and pulmonary vascular changes induced by intermittent hypoxia. Nitrendipine has anticancer effects on neuroblastoma .
Cat. No.: HY-B0284S
CAS No.: 1188266-14-9
Synonyms: BAY-a-1040-d6
Synonyms: 5,6-EET; (±)5,6-EpETrE
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Research Areas:
5,6-Epoxyeicosatrienoic acid (5,6-EET; (±)5,6-EpETrE) is a fully racemic version of the enantiomeric forms biosynthesized from arachidonic acid by cytochrome P450 enzymes. In solution, 5,6-Epoxyeicosatrienoic acid degrades into 5,6-DiHET and 5,6-δ-lactone, which can be converted to 5,6-DiHET and quantified by GC-MS. In neuroendocrine cells, such as the anterior pituitary and pancreatic islets, 5,6-Epoxyeicosatrienoic acid has been implicated in the mobilization of calcium and hormone secretion. 5,6-Epoxyeicosatrienoic acid is an inhibitor of T-type voltage-gated calcium channels (Cav3) that inhibits isoforms Cav3.1, Cav3.2 (IC50=0.54 μM), and Cav3. and decreases nifedipine-resistant phenylephrine-induced vasoconstriction in isolated mouse mesenteric arteries via Cav3.2 blockade when used at a concentration of 3 μM. In addition, it is a substrate of COX-1 and COX-2.
Cat. No.: HY-B0284R
CAS No.: 21829-25-4
Synonyms: BAY-a-1040 (Standard)
Research Areas:
Nifedipine (Standard) is the analytical standard of Nifedipine. This product is intended for research and analytical applications. Nifedipine (BAY-a-1040) is a potent calcium channel blocker and agent of choice for cardiac insufficiencies.
Cat. No.: HY-W019726
CAS No.: 67035-22-7
Synonyms: BAY-b 4759
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Research Areas:
Dehydro nifedipine (BAY-b 4759) is a metabolite of Nifedipine (HY-B0284). Nifedipine (BAY-a-1040) is a potent calcium channel blocker and an agent of choice for cardiac insufficiencies .
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Research Areas:
m-Nifedipine is an impurity of Nifedipine (BAY-a-1040). Nifedipine is a potent calcium channel blocker and agent of choice for cardiac insufficiencies .
Cat. No.: HY-B0424S
CAS No.: 2469554-26-3
Synonyms: AY-E-5009-d5
Cat. No.: HY-B0424R
CAS No.: 39562-70-4
Synonyms: BAY-E-5009 (Standard)
Research Areas:
Nitrendipine (Standard) is the analytical standard of Nitrendipine (HY-B0424). This product is intended for research and analytical applications. Nitrendipine (BAY-E-5009) is an orally active analog of Nifedipine (HY-B0284) and dihydropyridine calcium channel blocker. Nitrendipine induces Apoptosis. Nitrendipine has antihypertensive effects. Nitrendipine blocks alcohol and Morphine withdrawal symptoms. Nitrendipine reduces right ventricular hypertrophy and pulmonary vascular changes induced by intermittent hypoxia. Nitrendipine has anticancer effects on neuroblastoma .
Cat. No.: HY-139428
CAS No.: 34783-31-8
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Research Areas:
Hydroxydehydro Nifedipine Carboxylate is an inactive metabolite formed by the oxidative biotransformation of Nifedipine (HY-B0284) in the human body .
Cat. No.: HY-B0284A
CAS No.: 60299-11-8
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Research Areas:
Nifedipine hydrochloride is a potent vasodilator with calcium antagonist activity. Nifedipine hydrochloride is a useful antianginal compound that can also lower blood pressure. Nifedipine hydrochloride exhibits comparable antihypertensive properties to some new compounds, especially in calcium channel blockade. Nifedipine hydrochloride is used in biological activity studies to develop new antihypertensive and/or antianginal compounds .
Cat. No.: HY-135356R
CAS No.: 21881-77-6
Target:
Research Areas:
m-Nifedipine (Standard) is the analytical standard of m-Nifedipine. This product is intended for research and analytical applications. m-Nifedipine is an impurity of Nifedipine (BAY-a-1040). Nifedipine is a potent calcium channel blocker and agent of choice for cardiac insufficiencies .
Cat. No.: HY-B0284S1
CAS No.: 1219798-99-8
Synonyms: BAY-a-1040-d4
Cat. No.: HY-W019726S
CAS No.: 125464-52-0
Synonyms: BAY-b 4759-d6
Cat. No.: HY-W019726R
CAS No.: 67035-22-7
Synonyms: BAY-b 4759 (Standard)
Target:
Research Areas:
Dehydro Nifedipine (Standard) is the analytical standard of Dehydro Nifedipine. This product is intended for research and analytical applications. Dehydro nifedipine (BAY-b 4759) is a metabolite of Nifedipine (HY-B0284). Nifedipine (BAY-a-1040) is a potent calcium channel blocker and an agent of choice for cardiac insufficiencies .
Cat. No.: HY-D1759
Target:
Research Areas:
Fura-4F AM is a fluorescent dye used for detecting intracellular free calcium concentration ([Ca 2+]ᵢ). Fura-4F AM is cell membrane-permeable; after entering cells, it is hydrolyzed by intracellular esterases to form Fura-4F, and reflects changes in intracellular Ca 2+ concentration through Ca 2+ binding-dependent fluorescence changes, making it suitable for rapid detection of high-concentration Ca 2+ signals (Ex = 385 nm) .
Cat. No.: HY-B0284S2
CAS No.: 1173023-46-5
Synonyms: BAY-a-1040-13C8
Cat. No.: HY-W019726S1
CAS No.: 325484-33-1
Synonyms: BAY-b 4759-13C,d3
Cat. No.: HY-118674
CAS No.: 122508-12-7
Target:
Research Areas:
AK-2-38, a Nifedipine (HY-B0284) analogue, is a calcium channel antagonist. AK-2-38 also has partial agonist effects on isolated guinea pig left atrium .
Cat. No.: HY-Z13357S
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
