325484-33-1
325484-33-1
Chemical Structure
Dehydro Nifedipine-13C,d3
Synonym(s): BAY-b 4759-13C,d3
- CAS No.: 325484-33-1
- Formula:C913CH10D3N5O4
- Molecular Weight:271.25
InChIKey: HBOMLICNUCNMMY-JOUPVGMFSA-N
SMILES: O=C(C([13C]([2H])([2H])[2H])=CN1[C@@H](C2)O[C@@H]([C@H]2N=[N+]=[N-])CO)NC1=O
Biological Activity: Dehydro Nifedipine-13C,d3 is a deuterated labeled Dehydro Nifedipine[1]. Dehydro nifedipine (BAY-b 4759) is a metabolite of Nifedipine (HY-B0284). Nifedipine (BAY-a-1040) is a potent calcium channel blocker and an agent of choice for cardiac insufficiencies[2].
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Dehydro Nifedipine-13C,d3 | Dehydro Nifedipine-13C,d3 is a deuterated labeled Dehydro Nifedipine. Dehydro nifedipine (BAY-b 4759) is a metabolite of Nifedipine (HY-B0284). Nifedipine (BAY-a-1040) is a potent calcium channel blocker and an agent of choice for cardiac insufficiencies. | |||||||||||||||||||||
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References
- [1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216. [Content Brief]
- [2]. Dipanjan Goswami, et al. Method Development Challenges and Regulatory Expectation in Nifedipine. International Journal of Pharmacokinetics, Volume 2, 2017 - Issue 1.
Keywords
