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Nifedipine hydrochloride

29 Cited Publications
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Based on 29 publication(s) in Google Scholar

Nifedipine hydrochloride is a potent vasodilator with calcium antagonist activity. Nifedipine hydrochloride is a useful antianginal compound that can also lower blood pressure. Nifedipine hydrochloride exhibits comparable antihypertensive properties to some new compounds, especially in calcium channel blockade. Nifedipine hydrochloride is used in biological activity studies to develop new antihypertensive and/or antianginal compounds.

For research use only. We do not sell to patients.

  • CAS No.: 60299-11-8
  • Formula: C17H19ClN2O6
  • Molecular Weight:382.80
  • Storage:

    Please store the product under the recommended conditions in the Certificate of Analysis.

  • Nifedipine hydrochloride Chemical Structure
    Nifedipine hydrochloride Chemical Structure
  • Experimental Validation Results for Nifedipine hydrochloride
  • Experimental Validation Results for Nifedipine hydrochloride
  • Experimental Validation Results for Nifedipine hydrochloride
  • Experimental Validation Results for Nifedipine hydrochloride
  • Experimental Validation Results for Nifedipine hydrochloride
CAS No.: 60299-11-8
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  • Nifedipine hydrochloride Chemical Structure
    Nifedipine hydrochloride Chemical Structure
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    Nifedipine hydrochloride purchased from MedChemExpress. Usage Cited in: Alzheimers Res Ther. 2025 Dec 1;17(1):253. [Abstract]

    Customer Validation
     Nifedipine (5 µM, 1 min) decreased the neuronal cytoplasmic Ca2+ levels induced by 20 µM glutamate.

  • 1/16

    Nifedipine hydrochloride purchased from MedChemExpress. Usage Cited in: Pharmaceuticals (Basel). 2025 Sep 21;18(9):1420. [Abstract]

    Customer Validation
     Nifedipine (0.01 µM, 30 min) inhibited contractions induced by Ca2+ influx, keeping the contraction force below 0.1 g even at the highest calcium concentration of 10 mM.

  • 1/16

    Nifedipine hydrochloride purchased from MedChemExpress. Usage Cited in: Sci Signal. 2020 Nov 24;13(659):eaax0273. [Abstract]

    Customer Validation
     Nifedipine (10 µM, 30 min) relaxed 0.3 μM ACh-constricted mouse airways.

  • 1/16

    Nifedipine hydrochloride purchased from MedChemExpress. Usage Cited in: Sci Signal. 2020 Nov 24;13(659):eaax0273. [Abstract]

    Customer Validation
     Pretreatment with nifedipine (10 µM, 30 min) reduced ACh-induced airway constriction by about 25% but did not affect osthole-induced relaxation in mouse airways.

  • 1/16

    Nifedipine hydrochloride purchased from MedChemExpress. Usage Cited in: Front Endocrinol. 2018 Nov 30:9:721. [Abstract]

    Customer Validation
     Nifedipine (4 µM, 4 h) abolished the stimulation of Gh release by GnRH1 or GnRH3 in primary cultured pituitary cells from mixed-sex rice field eels.

  • Nifedipine hydrochloride