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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
8 Results for "
Nisoldipine
" in MedChemExpress (MCE) Product Catalog:
Products (8)
8 Results for "Nisoldipine" in MCE Product Catalog:
2
Research Areas:
Nisoldipine (BAY-k 5552; Sular) is an orally active and blood-brain barrier-penetrating dihydropyridine calcium antagonist, with greater vascular selectivity than other calcium channel antagonists. Nisoldipine inhibits calcium influx and blocks voltage-gated calcium channels. Nisoldipine dilates coronary and systemic arteries. Nisoldipine has antihypertensive and anti-anginal activity. Nisoldipine also displays neuroprotective and antiviral activity .
3
3 Cited Publications
Cat. No.: HY-Z0816
CAS No.: 87375-91-5
Target:
Research Areas:
Dehydronitrosonisoldipine, a derivative of Nisoldipine (HY-17402), is an irreversible and cell-permeant sterile alpha and TIR motif-containing 1 (SARM1) inhibitor. Dehydronitrosonisoldipine acts mainly by blocking SARM1 activation but not its enzymatic activities. Dehydronitrosonisoldipine inhibits SARM1 and axon degenration (AxD) by covalently modifying cysteines, also inhibits the Vincristine-activated cADPR production in neurons. Dehydronitrosonisoldipine can be used for researching neurodegenerative disorders .
Cat. No.: HY-17402S1
CAS No.: 1219795-47-7
Cat. No.: HY-17402S2
CAS No.: 1189718-34-0
Cat. No.: HY-17402S
CAS No.: 1285910-03-3
Synonyms: BAY-k 5552-d6
Cat. No.: HY-17402S3
CAS No.: 1432057-47-0
Synonyms: BAY-k 5552-d3
Cat. No.: HY-17402R
CAS No.: 63675-72-9
Synonyms: BAY-k 5552 (Standard)
Research Areas:
Nisoldipine (Standard) is the analytical standard of Nisoldipine. This product is intended for research and analytical applications. Nisoldipine (BAY-k 5552; Sular) is a highly efficient and specific L-type Cav1.2 channel blocker with an IC50 of 10 nM.
Cat. No.: HY-W184837
CAS No.: 113578-26-0
Synonyms: KR-1008
Target:
Research Areas:
m-Nisoldipine (KR-1008) is a dihydropyridine calcium antagonist that can significantly increase cardiac output and heart index, significantly reduce the negative inotropic effect on the myocardium, and has a relatively high selectivity for the thoracic aorta. m-Nisoldipine can be used in the research of cardiovascular diseases .
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Protocols
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