113578-26-0
Chemical Structure
m-Nisoldipine
Synonym(s): KR-1008
- CAS No.: 113578-26-0
- Formula:C20H24N2O6
- Molecular Weight:388.41
IUPAC Name: 3-isobutyl 5-methyl 2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate
InChIKey: MRSJBSHLMOBYSH-UHFFFAOYSA-N
SMILES: O=C(C1=C(C)NC(C)=C(C(OCC(C)C)=O)C1C2=CC=CC([N+]([O-])=O)=C2)OC
Biological Activity: m-Nisoldipine (KR-1008) is a dihydropyridine calcium antagonist that can significantly increase cardiac output and heart index, significantly reduce the negative inotropic effect on the myocardium, and has a relatively high selectivity for the thoracic aorta. m-Nisoldipine can be used in the research of cardiovascular diseases[1].
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m-Nisoldipine | m-Nisoldipine (KR-1008) is a dihydropyridine calcium antagonist that can significantly increase cardiac output and heart index, significantly reduce the negative inotropic effect on the myocardium, and has a relatively high selectivity for the thoracic aorta. m-Nisoldipine can be used in the research of cardiovascular diseases. | |||||||||||||||||||||
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Keywords