1 Result for "

OR502

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "OR502" in MCE Product Catalog:

Cat. No.: HY-P992433
Target:  

LILRB

Research Areas:  

Cancer

OR502 is a humanized IgG1 monoclonal antibody targeting LILRB2 (ILT4/CD85d), with a Kd value of 1.18 nM. OR502 binds to LILRB2 with high affinity and blocks its interaction with HLA class I ligands, relieving myeloid cell-mediated immunosuppression, restoring CD8 + T cell function, and reprogramming the immunosuppressive macrophage phenotype, thereby simultaneously enhancing both innate and adaptive antitumor immune responses. OR502 can be used in the research of cancers and advanced cancers (including melanoma, non-small cell lung cancer, sarcoma/soft tissue cancer, and urothelial carcinoma) .
loading...
    loading...