1 Result for "

PI3Kα-IN-27

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "PI3Kα-IN-27" in MCE Product Catalog:

Cat. No.: HY-178812
CAS No.: 2098649-83-1
Target:  

PI3K PAK mTOR PERK Apoptosis

Research Areas:  

Cancer

PI3Kα-IN-27 (Compound 50b) is an orally active PI3K-α inhibitor, with an IC50 of 40 nM. PI3Kα-IN-27 effectively inhibits PAK3, p110α, phospho-mTOR and phospho-ERK1/2. PI3Kα-IN-27 induces early Apoptosis. PI3Kα-IN-27 shows anticancer activity against pancreatic cancer, lung cancer, breast cancer .
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