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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
21 Results for "
PTI
" in MedChemExpress (MCE) Product Catalog:
Products (21)
21 Results for "PTI" in MCE Product Catalog:
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6
2
Research Areas:
Nesolicaftor (PTI-428) is a specific cystic fibrosis transmembrane conductance regulator (CFTR) amplifier .
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Target:
Research Areas:
Neurological Disease Metabolic Disease Inflammation/Immunology Cancer
Simufilam (PTI-125) is an orally active FLNA modulator. Simufilam restores NMDAR signaling and Arc expression. Simufilam inhibits overactive mTOR signaling by restoring the normal conformation of FLNA, improves insulin sensitivity, reduces Aβ42-induced neuroinflammation and tau protein hyperphosphorylation.
Simufilam can be used for research of Alzheimer's disease .
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1 Cited Publications
Synonyms: PTI-801 sodium
Target:
Research Areas:
Posenacaftor (PTI-801) sodium is a cystic fibrosis transmembrane regulator (CFTR) protein modulator that corrects the folding and trafficking of CFTR protein. Posenacaftor sodium is used for the research of cystic fibrosis (CF) .
1
1 Cited Publications
Synonyms: PTI-125 hydrochloride
Target:
Research Areas:
Neurological Disease Metabolic Disease Inflammation/Immunology Cancer
Simufilam hydrochloride (PTI-125 hydrochloride) is an orally active FLNA modulator. Simufilam hydrochloride restores NMDAR signaling and Arc expression. Simufilam hydrochloride inhibits overactive mTOR signaling by restoring the normal conformation of FLNA, improves insulin sensitivity, reduces Aβ42-induced neuroinflammation and tau protein hyperphosphorylation. Simufilam hydrochloride can be used for research of Alzheimer's disease .
Cat. No.: HY-139142A
CAS No.: 2480226-06-8
Synonyms: PTI-125 dihydrochloride
Target:
Research Areas:
Simufilam dihydrochloride (PTI-125 dihydrochloride) is an orally active FLNA modulator. Simufilam dihydrochloride restores NMDAR signaling and Arc expression. Simufilam dihydrochloride inhibits overactive mTOR signaling by restoring the normal conformation of FLNA, improves insulin sensitivity, reduces Aβ42-induced neuroinflammation and tau protein hyperphosphorylation. Simufilam dihydrochloride can be used for research of Alzheimer's disease .
Synonyms: (R)-PTI-801 sodium
Target:
Research Areas:
(R)-Posenacaftor (R)-PTI-801) sodium is the R enantiomer of Posenacaftor. Posenacaftor is a cystic fibrosis transmembrane regulator (CFTR) protein modulator that corrects the folding and trafficking of CFTR protein. Posenacaftor is used for the research of cystic fibrosis (CF) .
Cat. No.: HY-109187
CAS No.: 2095064-05-2
Synonyms: PTI-801
Target:
Research Areas:
Posenacaftor (PTI-801) is a cystic fibrosis transmembrane regulator (CFTR) protein modulator that corrects the folding and trafficking of CFTR protein. Posenacaftor is used for the research of cystic fibrosis (CF) .
Cat. No.: HY-129821
CAS No.: 1400742-46-2
Target:
Research Areas:
PTI-1 is a synthetic cannabinoid (CB) that contains the 1-pentyl-indole structure.
Cat. No.: HY-RS12714
Target:
Research Areas:
SERPINB6 Human Pre-designed siRNA Set A contains three designed siRNAs for SERPINB6 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-111680R
CAS No.: 1953130-87-4
Synonyms: PTI-428 (Standard)
Target:
Research Areas:
Nesolicaftor (Standard) is the analytical standard of Nesolicaftor (HY-111680). This product is intended for research and analytical applications. Nesolicaftor (PTI-428) is a specific cystic fibrosis transmembrane conductance regulator (CFTR) amplifier .
Cat. No.: HY-109187AR
CAS No.: 2095064-06-3
Synonyms: PTI-801 sodium (Standard)
Target:
Research Areas:
Posenacaftor sodium (Standard) is the analytical standard of Posenacaftor (sodium) (HY-109187A). This product is intended for research and analytical applications. Posenacaftor (PTI-801) sodium is a cystic fibrosis transmembrane regulator (CFTR) protein modulator that corrects the folding and trafficKing of CFTR protein. Posenacaftor sodium is used for the research of cystic fibrosis (CF) .
Cat. No.: HY-109187BR
CAS No.: 2095064-09-6
Synonyms: (R)-PTI-801 sodium (Standard)
Target:
Research Areas:
(R)-Posenacaftor sodium (Standard) is the analytical standard of (R)-Posenacaftor (sodium) (HY-109187B). This product is intended for research and analytical applications. (R)-Posenacaftor (R)-PTI-801) sodium is the R enantiomer of Posenacaftor. Posenacaftor is a cystic fibrosis transmembrane regulator (CFTR) protein modulator that corrects the folding and trafficKing of CFTR protein. Posenacaftor is used for the research of cystic fibrosis (CF) .
Cat. No.: HY-P70970
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: SERPINB6; Serpin PePTIdase Inhibitor, Clade B (Ovalbumin), Member 6; Prev. PI6; PI-6; Prev. DFNB91; Protease Inhibitor 6 (Placental Thrombin Inhibitor); PTI; Deafness, Autosomal Recessive 91; CAP; PePTIdase Inhibitor 6; Cytoplasmic Antiproteinase; MSTP057
Cat. No.: HY-P76640
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: SERPINB6; Serpin PePTIdase Inhibitor, Clade B (Ovalbumin), Member 6; Prev. PI6; PI-6; Prev. DFNB91; Protease Inhibitor 6 (Placental Thrombin Inhibitor); PTI; Deafness, Autosomal Recessive 91; CAP; PePTIdase Inhibitor 6; Cytoplasmic Antiproteinase; MSTP057
Species:
Source:
Cat. No.: HY-183624
CAS No.: 1258530-99-2
Trimer44NMe is a polyamine transport inhibitor (PTI). Trimer44NMe inhibits the polyamine transport of putrescine (Put), spermidine (Spd), and spermine (Spm). Trimer44NMe can be used for research of Pancreatic ductal adenocarcinoma (PDAC) .
Cat. No.: HY-P88442A
Synonyms: CAP; DFNB91; MSTP057; PI-6; PI6; PTI; SPI3
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
