SERPINB6 Antibody (YA8126)(PBS only)

Cat. No.: HY-P88442A: Data Sheet User Guide for Antibodies
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SERPINB6 Antibody (YA8126) is a Mouse-derived and non-conjugated IgG2a monoclonal antibody, targeting to SERPINB6.

For research use only. We do not sell to patients.

Size		Stock
50 μL		Get quote
100 μL		Get quote

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WB: Western Blot;
IHC-P: Immunohistochemistry-Paraffin;
IHC-F: Immunohistochemistry-Frozen;
ICC/IF: Immunocytochemistry/Immunofluorescence;
IF-Tissue: Immunofluorescence-Tissue;
mIHC: Multiplex Immunohistochemical;
IP: Immunoprecipitation;
ChIP: Chromatin Immunoprecipitation;
FC: Flow Cytometry;
ELISA: Enzyme Linked Immunosorbent Assay

Product Detail
Background
Documentation

Description

SERPINB6 Antibody (YA8126) is a Mouse-derived and non-conjugated IgG2a monoclonal antibody, targeting to SERPINB6.

Host

Mouse

Molecular Weight

Predicted band size: 42.4 kDa

Species Reactivity

Human

SwissProt ID

P35237

Immunogen

Full length human recombinant protein of human SERPINB6 produced in HEK293T cell.

Application &
Dilution Ratio

Application	Dilution Ratio
ICC/IF ICC/IF: Immunocytochemistry/Immunofluorescence	1:100-250
FC FC: Flow Cytometry	1:100

Purity	Affinity purified	Conjugation	Non-conjugated
Isotype	IgG2a

Appearance

Solution

Formulation

Supplied in PBS, pH 7.4.

Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

Shipping

Shipping with blue ice.

Background

Function：May be involved in the regulation of serine proteinases present in the brain or extravasated from the blood (By similarity). Inhibitor of cathepsin G, kallikrein-8 and thrombin. May play an important role in the inner ear in the protection against leakage of lysosomal content during stress and loss of this protection results in cell death and sensorineural hearing loss

Subcellular Localization：Cytoplasm

Expression：
Tissue_Specificity: Expressed in keratinocytes (at protein level). Highest levels in skeletal muscle. Also found in placenta, cardiac muscle, lung, liver, kidney and pancreas. Expressed in the inner ear hair cells. Expressed abundantly by normal mast cells in different tissues and by mast cells in mastocytoma lesions

Isoforms & Post-Translational Modification：P35237: 376 amino acids, molecular weight 42622 Da.

Subunit：Forms a complex with the monomeric form of beta-tryptase

Synonyms

CAP; DFNB91; MSTP057; PI-6; PI6; PTI; SPI3

Documentation

User Guide for Antibodies (1077 KB)