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  3. Cancer Digestive System Disease
  4. Pancreatic Cancer Digestive System Cancer
  5. Trimer44NMe

Trimer44NMe is a polyamine transport inhibitor (PTI). Trimer44NMe inhibits the polyamine transport of putrescine (Put), spermidine (Spd), and spermine (Spm). Trimer44NMe can be used for research of Pancreatic ductal adenocarcinoma (PDAC).

For research use only. We do not sell to patients.

Trimer44NMe

Trimer44NMe Chemical Structure

CAS No. : 1258530-99-2

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Trimer44NMe Related Antibodies

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Description

Trimer44NMe is a polyamine transport inhibitor (PTI). Trimer44NMe inhibits the polyamine transport of putrescine (Put), spermidine (Spd), and spermine (Spm). Trimer44NMe can be used for research of Pancreatic ductal adenocarcinoma (PDAC)[1][2].

In Vitro

Trimer44NMe inhibits the polyamine transport of putrescine (Put), spermidine (Spd), and spermine (Spm) with Ki of 17.4, 2.6, and 0.9 μM, respectively[2].
Trimer44NMe (72 h) exhibits cytotoxicity against human pancreatic cancer cells (L3.6pl) with a maximum tolerated concentration (MTC) of 3 μM and an IC50 of 50 μM[2].
Trimer44NMe (3-10 μM, 15 min) inhibits radiolabeled polyamine uptake in L3.6pl cells[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Trimer44NMe Related Antibodies
Molecular Weight

634.04

Formula

C36H75N9
CAS No.
SMILES

CNCCCCNCCCCNCC1=CC(CNCCCCNCCCCNC)=CC(CNCCCCNCCCCNC)=C1
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Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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Trimer44NMe Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Trimer44NMe1258530-99-2OthersL3.6plPDACputrescinespermidinespermineInhibitorinhibitorinhibit

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