1258530-99-2
1258530-99-2
Chemical Structure
Trimer44NMe
- CAS No.: 1258530-99-2
- Formula:C36H75N9
- Molecular Weight:634.04
InChIKey: RVJGJAFNXCBYCC-UHFFFAOYSA-N
SMILES: CNCCCCNCCCCNCC1=CC(CNCCCCNCCCCNC)=CC(CNCCCCNCCCCNC)=C1
Biological Activity: Trimer44NMe is a polyamine transport inhibitor (PTI). Trimer44NMe inhibits the polyamine transport of putrescine (Put), spermidine (Spd), and spermine (Spm). Trimer44NMe can be used for research of Pancreatic ductal adenocarcinoma (PDAC)[1][2].
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Trimer44NMe | Trimer44NMe is a polyamine transport inhibitor (PTI). Trimer44NMe inhibits the polyamine transport of putrescine (Put), spermidine (Spd), and spermine (Spm). Trimer44NMe can be used for research of Pancreatic ductal adenocarcinoma (PDAC). | |||||||||||||||||||||
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References
- [1]. Wang M, et al. Evaluation of Polyamine Transport Inhibitors in a Drosophila Epithelial Model Suggests the Existence of Multiple Transport Systems. Med. Sci. 2017, 5, 27.
- [2]. Dobrovolskaite A, et al. Development of Polyamine Lassos as Polyamine Transport Inhibitors. ACS Med Chem Lett. 2022 Jan 20;13(2):319-326. [Content Brief]
Keywords
