Nesolicaftor (Standard)
Nesolicaftor (Standard) is the analytical standard of Nesolicaftor (HY-111680). This product is intended for research and analytical applications. Nesolicaftor (PTI-428) is a specific cystic fibrosis transmembrane conductance regulator (CFTR) amplifier.
For research use only. We do not sell to patients.
- CAS No.: 1953130-87-4
- Formula: C18H18N4O4
- Molecular Weight:354.36
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Product Information
Information
Application
The compound is the grade of analytical standard, which is the reference standard supplied assay. It is commonly used in qualitative, quantitative and methodological research experiments in HPLC, GC and MS.
Chemical Information
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CAS No. 1953130-87-4
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Molecular Weight 354.36
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Formula C18H18N4O4
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SMILES
O=C(C1=CC(C2=CC=CC=C2)=NO1)N[C@H]3C[C@H](C4=NN=C([C@H](O)C)O4)C3
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Synonyms
PTI-428 (Standard)
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
[1]. Mijnders M, et al. Correcting CFTR folding defects by small-molecule correctors to cure cystic fibrosis. Curr Opin Pharmacol. 2017 Jun;34:83-90. [Content Brief]
[2]. Arianna Venturini, et al. Comprehensive Analysis of Combinatorial Pharmacological Treatments to Correct Nonsense Mutations in the CFTR Gene. Int J Mol Sci. 2021 Nov 4;22(21):11972. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)