SERPINB6 Antibody (YA8126)
(Synonyms: CAP; DFNB91; MSTP057; PI-6; PI6; PTI; SPI3)SERPINB6 Antibody (YA8126) is a Mouse-derived and non-conjugated IgG2a monoclonal antibody, targeting to SERPINB6.
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Host:
Mouse
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Isotype:
IgG2a
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Application:
ICC/IF, FC
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Reactivity :
Human
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Formulation:
Spplied in PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
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Conjugation:
Non-conjugated
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Applications
| Application |
ICC/IF
ICC/IF: Immunocytochemistry/
Immunofluorescence |
FC
FC: Flow Cytometry
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|---|---|---|
| Dilution Ratio | 1:100-250 | 1:100 |
Product Details
SERPINB6 Antibody (YA8126) is a Mouse-derived and non-conjugated IgG2a monoclonal antibody, targeting to SERPINB6.
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Host Mouse
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Clonality Monoclonal
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Species ReactivityHuman
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Calculated Molecular Weight Predicted band size: 42.4 kDa
Full length human recombinant protein of human SERPINB6 produced in HEK293T cell.
Endogenous
Affinity purified
Non-conjugated
Unmodified
IgG2a
Product Properties
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Appearance
Solution
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Formulation
Spplied in PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
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Storage & Stability
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
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Shipping
Shipping with blue ice.
Background
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Function
SERPINB6 may be involved in the regulation of serine proteinases present in the brain or extravasated from the blood. Inhibitor of cathepsin G, kallikrein-8 and thrombin. May play an important role in the inner ear in the protection against leakage of lysosomal content during stress and loss of this protection results in cell death and sensorineural hearing loss
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Subcellular Localization
Cytoplasm
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Expression
Tissue_Specificity: Expressed in keratinocytes (at protein level). Highest levels in skeletal muscle. Also found in placenta, cardiac muscle, lung, liver, kidney and pancreas. Expressed in the inner ear hair cells. Expressed abundantly by normal mast cells in different tissues and by mast cells in mastocytoma lesions -
Isoforms & Post-Translational Modification
P35237: 376 amino acids, molecular weight 42622 Da.
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Subunit
Forms a complex with the monomeric form of beta-tryptase
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SwissProt ID
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Synonyms
CAP; DFNB91; MSTP057; PI-6; PI6; PTI; SPI3
Documentation
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