2. Search Result
Search Result
Results for "

Pinoresinol

" in MedChemExpress (MCE) Product Catalog:

17

Inhibitors & Agonists

17

Natural
Products

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-N0657
    Pinoresinol Diglucoside
    1 Publications Verification

    		 NF-κB Keap1-Nrf2 Heme Oxygenase (HO) TGF-beta/Smad Akt mTOR PI3K Cardiovascular Disease Neurological Disease Metabolic Disease Inflammation/Immunology
    Pinoresinol Diglucoside is an orally active lignan with multifunctional bioactivity. Pinoresinol Diglucoside interacts with targets including ALB, HIF1A, GSK3B, BCL2, MARK3, IL6, NF-κB p65, Nrf2, HO-1, and TLR4, and modulates pathways including PI3K-Akt, estrogen, MAPK, Rap1, AKT/mTOR/NF-κB, and TGF-β1/Smads. Pinoresinol Diglucoside regulates osteogenesis, bone resorption, oxidative stress, inflammation, apoptosis, ferroptosis, ferritinophagy, cardiac fibrosis, and vasorelaxation. Pinoresinol Diglucoside can be used for the research of osteoporosis, ischemia/reperfusion-induced brain injury, Alzheimer’s disease, myocardial ischemia-reperfusion injury, chondrodysplasia, diabetic cardiomyopathy, cardiac hypertrophy, hypertension, cisplatin-induced hearing loss, atherosclerotic cardiovascular diseases, and disuse osteoporosis .
    Pinoresinol Diglucoside
  • HY-N6253
    Pinoresinol
    1 Publications Verification

    (+)-Pinoresinol

    		 Apoptosis Cancer
    Pinoresinol is a lignol of plant origin serving for defense in a caterpillar. Pinoresinol drastically sensitizes cancer cells against TNF-related apoptosis-inducing ligand (TRAIL) -induced apoptosis .
    Pinoresinol
  • HY-126067
    (-)-Pinoresinol

    		Glycosidase Apoptosis Inflammation/Immunology
    (-)-Pinoresinol is a plant-derived tetrahydrofuran lignan that inhibits α-glucosidase and acts as a hypoglycemic agent. (-)-Pinoresinol has some anti-inflammatory effects and acts as a chemopreventive agent, inducing increased apoptosis and cell cycle G2/M arrest .
    (-)-Pinoresinol
  • HY-N2168
    Pinoresinol 4-O-β-D-glucopyranoside
    1 Publications Verification

    (+)-Pinoresinol 4-O-β-D-glucopyranoside

    		 Glycosidase Estrogen Receptor/ERR Phosphodiesterase (PDE) Neurological Disease Metabolic Disease Cancer
    Pinoresinol 4-O-β-D-glucopyranoside ((+)-Pinoresinol 4-O-β-D-glucopyranoside) is an orally active α-glucosidase inhibitor, with an IC50 of 48.13 μg/mL. Pinoresinol 4-O-β-D-glucopyranoside binds to estrogen receptors. Pinoresinol 4-O-β-D-glucopyranoside inhibits phosphodiesterase. Pinoresinol 4-O-β-D-glucopyranoside exhibits various activities such as antioxidant, anti-inflammatory, anti-hyperglycemic, hepatoprotective and anti-epileptic effects .
    Pinoresinol 4-O-β-D-glucopyranoside
  • HY-N2180
    (+)-Eudesmin

    (+)-Eudesmine

    		 PKC PKA p38 MAPK NO Synthase Neurological Disease
    Pinoresinol dimethyl ether ((+)-Eudesmin) is a non-phenolic furanoid lignin. Pinoresinol dimethyl ether can be isolated from Magnolia biondii. Pinoresinol dimethyl ether activates MAPK, PKC, and PKA upstream pathways and inhibits NO levels. Pinoresinol dimethyl ether has neuroprotective activity .
    (+)-Eudesmin
  • HY-N0946
    (-)-Pinoresinol 4-O-glucoside

    (-)-Pinoresinol 4-O-β-D-glucopyranoside

    		 Glycosidase Metabolic Disease
    (-)-Pinoresinol 4-O-glucoside ((-)-Pinoresinol 4-O-β-D-glucopyranoside) is a potent and orally active α-glucosidase inhibitor with an IC50 value of 48.13 µM. (-)-Pinoresinol 4-O-glucoside increases cell migration and early differentiation of pre-osteoblasts. (-)-Pinoresinol 4-O-glucoside increases protein level of BMP2, p-Smad1/5/8, RUNX2. (-)-Pinoresinol 4-O-glucoside attenuates oxidative stress, hyperglycemia and hepatic toxicity. (-)-Pinoresinol 4-O-glucoside has the potential for the research of osteoporosis and periodontal disease .
    (-)-Pinoresinol 4-O-glucoside
  • HY-N6253R
    Pinoresinol (Standard)

    (+)-Pinoresinol (Standard)

    		 Reference Standards Apoptosis Cancer
    Pinoresinol (Standard) is the analytical standard of Pinoresinol. This product is intended for research and analytical applications. Pinoresinol is a lignol of plant origin serving for defense in a caterpillar. Pinoresinol drastically sensitizes cancer cells against TNF-related apoptosis-inducing ligand (TRAIL) -induced apoptosis .
    Pinoresinol (Standard)
  • HY-N0957
    (±)-Pinoresinol

    		Fungal Infection
    (±)-Pinoresinol is a potent antifungal agent. (±)-Pinoresinol shows antifungal activity .
    (±)-Pinoresinol
  • HY-N16589
    (-)-Isolariciresinol

    		Others Others
    (-)-Isolariciresinol is a type of lignan that can be found in Flaxseed Meal .
    (-)-Isolariciresinol
  • HY-N0954
    (+)-Pinoresinol diacetate

    		Fungal Infection Inflammation/Immunology
    (+)-Pinoresinol diacetate is an antifungal agent that can be isolated from Sambucus williamsii .
    (+)-Pinoresinol diacetate
  • HY-N0657R
    Pinoresinol Diglucoside (Standard)

    		Reference Standards NF-κB Keap1-Nrf2 Heme Oxygenase (HO) TGF-beta/Smad Akt mTOR PI3K Cardiovascular Disease Neurological Disease Metabolic Disease Inflammation/Immunology
    Pinoresinol Diglucoside (Standard) is the analytical standard of Pinoresinol Diglucoside (HY-N0657). This product is intended for research and analytical applications. Pinoresinol Diglucoside is an orally active lignan with multifunctional bioactivity. Pinoresinol Diglucoside interacts with targets including ALB, HIF1A, GSK3B, BCL2, MARK3, IL6, NF-κB p65, Nrf2, HO-1, and TLR4, and modulates pathways including PI3K-Akt, estrogen, MAPK, Rap1, AKT/mTOR/NF-κB, and TGF-β1/Smads. Pinoresinol Diglucoside regulates osteogenesis, bone resorption, oxidative stress, inflammation, apoptosis, ferroptosis, ferritinophagy, cardiac fibrosis, and vasorelaxation. Pinoresinol Diglucoside can be used for the research of osteoporosis, ischemia/reperfusion-induced brain injury, Alzheimer’s disease, myocardial ischemia-reperfusion injury, chondrodysplasia, diabetic cardiomyopathy, cardiac hypertrophy, hypertension, cisplatin-induced hearing loss, atherosclerotic cardiovascular diseases, and disuse osteoporosis.
    Pinoresinol Diglucoside (Standard)
  • HY-N2168R
    Pinoresinol 4-O-β-D-glucopyranoside (Standard)

    (+)-Pinoresinol 4-O-β-D-glucopyranoside (Standard)

    		 Glycosidase Reference Standards Estrogen Receptor/ERR Phosphodiesterase (PDE) Neurological Disease Metabolic Disease Cancer
    Pinoresinol 4-O-β-D-glucopyranoside (Standard) is the analytical standard of Pinoresinol 4-O-β-D-glucopyranoside (HY-N2168). This product is intended for research and analytical applications. Pinoresinol 4-O-β-D-glucopyranoside is an orally active α-glucosidase inhibitor, with an IC50 of 48.13 μg/mL. Pinoresinol 4-O-β-D-glucopyranoside binds to estrogen receptors. Pinoresinol 4-O-β-D-glucopyranoside inhibits phosphodiesterase. Pinoresinol 4-O-β-D-glucopyranoside exhibits various activities such as antioxidant, anti-inflammatory, anti-hyperglycemic, hepatoprotective and anti-epileptic effects .
    Pinoresinol 4-O-β-D-glucopyranoside (Standard)
  • HY-N7982
    (+)-Pinoresinol monomethyl ether O-β-D-glucoside

    		Others Others
    (+)-Pinoresinol monomethyl ether O-β-D-glucoside (Compound 6) is a natural product that can be isolated from the stems of Tinospora sinensis .
    (+)-Pinoresinol monomethyl ether O-β-D-glucoside
  • HY-N2180R
    (+)-Eudesmin (Standard)

    (+)-Eudesmine (Standard)

    		 Reference Standards PKC PKA p38 MAPK NO Synthase Neurological Disease
    Pinoresinol dimethyl ether (Standard) is the analytical standard of Pinoresinol dimethyl ether (HY-N2180). This product is intended for research and analytical applications. Pinoresinol dimethyl ether ((+)-Eudesmin) is a non-phenolic furanoid lignin. Pinoresinol dimethyl ether can be isolated from Magnolia biondii. Pinoresinol dimethyl ether activates MAPK, PKC, and PKA upstream pathways and inhibits NO levels. Pinoresinol dimethyl ether has neuroprotective activity .
    (+)-Eudesmin (Standard)
  • HY-N1189
    DL-Syringaresinol diacetate

    Syringaresinol Diacetate

    		 Others Cancer
    DL-Syringaresinol diacetate is a glucoside. DL-Syringaresinol inhibits cAMP phosphodiesterase and alleviation of stress .
    DL-Syringaresinol diacetate
  • HY-N17513
    4'-Methoxy-pinoresinol

    		Drug Derivative Others
    4'-Methoxy-pinoresinol is a natural product that can be found in Forsythia suspensa?(Thunb.) Vahl.
    4'-Methoxy-pinoresinol
  • HY-N17896
    Pinoresinol-4-O-β-D-apiosyl-(1→2)β-D-glucoside

    		Tyrosinase Cancer
    Pinoresinol-4-O-β-D-apiosyl-(1→2)β-D-glucoside is a lignan compound and a melanogenesis inhibitor with low cytotoxicity. Pinoresinol-4-O-β-D-apiosyl-(1→2)β-D-glucoside is isolable from the stem bark of Acer buergerianum (Acer buergerianum). Pinoresinol-4-O-β-D-apiosyl-(1→2)β-D-glucoside effectively inhibits the melanogenesis process in α-MSH (HY-P0252)-stimulated B16 melanoma cells. Pinoresinol-4-O-β-D-apiosyl-(1→2)β-D-glucoside exhibits extremely high safety towards normal cells, and serves as an ideal tool molecule for studying melanoma mechanisms and developing related whitening products .
    Pinoresinol-4-O-β-D-apiosyl-(1→2)β-D-glucoside

Inquiry Online

Your information is safe with us. * Required Fields.

Salutation

  

Country or Region *

Applicant Name *

 

Organization Name *

Department *

     

Email Address *

 

Product Name *

Cat. No.

  

Requested quantity *

Phone Number *

     

Remarks

Inquiry Online

Inquiry Information

Product Name:
Cat. No.:
Quantity:
MCE Japan Authorized Agent: