487-36-5
487-36-5
Chemical Structure
Pinoresinol
Synonym(s): (+)-Pinoresinol
- CAS. Nr.: 487-36-5
- Formula:C20H22O6
- Molecular Weight:358.39
IUPAC Name: 4,4'-((1S,3aR,4S,6aR)-tetrahydro-1H,3H-furo[3,4-c]furan-1,4-diyl)bis(2-methoxyphenol)
InChIKey: HGXBRUKMWQGOIE-AFHBHXEDSA-N
SMILES: COC1=C(O)C=CC([C@@H]2[C@]3([H])[C@]([C@@H](C4=CC(OC)=C(O)C=C4)OC3)([H])CO2)=C1
Biological Activity: Pinoresinol is a lignol of plant origin serving for defense in a caterpillar. Pinoresinol drastically sensitizes cancer cells against TNF-related apoptosis-inducing ligand (TRAIL) -induced apoptosis[1][2].
| Art. -Nr. | Produktname | Reinheit | Beschreibung | Pricing | |||||||||||||||||||
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Pinoresinol | 99.48% | Pinoresinol is a lignol of plant origin serving for defense in a caterpillar. Pinoresinol drastically sensitizes cancer cells against TNF-related apoptosis-inducing ligand (TRAIL) -induced apoptosis. | ||||||||||||||||||||
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Pinoresinol (Standard) | ≥98% | Pinoresinol (Standard) is the analytical standard of Pinoresinol. This product is intended for research and analytical applications. Pinoresinol is a lignol of plant origin serving for defense in a caterpillar. Pinoresinol drastically sensitizes cancer cells against TNF-related apoptosis-inducing ligand (TRAIL) -induced apoptosis. | ||||||||||||||||||||
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(-)-Pinoresinol | 99.83% | (-)-Pinoresinol is a plant-derived tetrahydrofuran lignan that inhibits α-glucosidase and acts as a hypoglycemic agent. (-)-Pinoresinol has some anti-inflammatory effects and acts as a chemopreventive agent, inducing increased apoptosis and cell cycle G2/M arrest. | ||||||||||||||||||||
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Phillygenin | 98.55% | Phillygenin (Phillygenol) is an active ingredient from Forsythia with many medicinal properties, such as antioxidant, reducing blood lipid, inhibition of low density lipoprotein oxidation. | ||||||||||||||||||||
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(±)-Pinoresinol | (±)-Pinoresinol is a potent antifungal agent. (±)-Pinoresinol shows antifungal activity. | |||||||||||||||||||||
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rel-Medioresinol | rel-Medioresinol is a natural lignan. | |||||||||||||||||||||
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4'-Methoxy-pinoresinol | 4'-Methoxy-pinoresinol is a natural product that can be found in Forsythia suspensa?(Thunb.) Vahl. | |||||||||||||||||||||
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(+)-Medioresinol | 99.13% | (+)-Medioresinol is a furofuran-type lignan with antifungal and antibacterial properties. (+)-Medioresinol synergizes with antibiotics to exert antimicrobial and antibiofilm effects. (+)-Medioresinol induces intracellular ROS accumulation and mitochondrial-mediated apoptosis in Candida albicans. (+)-Medioresinol inhibits LPS (HY-D1056)-stimulated IL-12p40 production. (+)-Medioresinol is a PGC-1α activator that protects against endothelial cell pyroptosis in ischemic stroke via the PPARα-GOT1 axis. (+)-Medioresinol can be used in research on fungal and bacterial infection, inflammation, and ischemic stroke. | ||||||||||||||||||||
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Clemaphenol A | 99.77% | Clemaphenol A is a chemical constituent of the flower of Fritillaria pallidiflora. | ||||||||||||||||||||
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(+)-Epipinoresinol | 98.12% | (+)-Epipinoresinol is a lignan compound. CYP81Q3 specifically catalyzes methylenedioxy bridge (MDB) formation in (+)-Epipinoresinol to produce (+)-Pluviatilol. | ||||||||||||||||||||
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(-)-Epipinoresinol | (-)-Epipinoresinol is an isomer of the lignan (+)-Epipinoresinol. CYP81Q3 specifically catalyzes the formation of the methylenedioxy bridge (MDB) in (+)-Epipinoresinol to produce (+)-Pluviatilol. | |||||||||||||||||||||
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(rel)-Epipinoresinol | (rel)-Epipinoresinol is a natural product that can be found in Forsythia suspensa?(Thunb.) Vahl. | |||||||||||||||||||||
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References
- [1]. Schroeder FC, et al. Pinoresinol: A lignol of plant origin serving for defense in a caterpillar. Proc Natl Acad Sci U S A. 2006 Oct 17;103(42):15497-501. [Content Brief]
- [2]. Lee SR, et al. Accelerated degradation of cFLIPL and sensitization of the TRAIL DISC-mediated apoptotic cascade by pinoresinol, a lignan isolated from Rubia philippinensis. Sci Rep. 2019 Sep 18;9(1):13505. [Content Brief]
