5 Results for "

Purvalanol B

" in MedChemExpress (MCE) Product Catalog:
Products (5)

5 Results for "Purvalanol B" in MCE Product Catalog:

2
2 Cited Publications
Cat. No.: HY-18299
CAS No.: 212844-54-7
Synonyms: NG 95
Target:  

CDK Parasite

Research Areas:  

Infection Cancer

Purvalanol B (NG 95) is a potent, selective, reversible and ATP-competitive inhibitor CDK, with IC50s of 6 nM, 6 nM, 9 nM, 6 nM for cdc2-cyclin B, CDK2-cyclin A, CDK2-cyclin E and CDK5-p35, respectively. Purvalanol B shows selectivity for CDK over a range of other protein kinases (IC50>1000 nM). Purvalanol B inhibits the growth a chloroquine-resistant strain of P. falciparum .
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4
4 Cited Publications
Cat. No.: HY-18299A
CAS No.: 212844-53-6
Synonyms: NG-60
Target:  

CDK Autophagy Apoptosis

Research Areas:  

Cancer

Purvalanol A is a potent CDK inhibitor, which inhibits cdc2-cyclin B, cdk2-cyclin A, cdk2-cyclin E, cdk4-cyclin D1, and cdk5-p35 with IC50s of 4, 70, 35, 850, 75 nM, resepctively.
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Cat. No.: HY-18299B
CAS No.: 2310135-61-4
Synonyms: (S)-NG 95
Target:  

Drug Isomer

Research Areas:  

Others

(S)-Purvalanol B is the S enantiomer of Purvalanol B. Purvalanol B is a cyclin-dependent kinase inhibitor.
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Cat. No.: HY-18299AR
CAS No.: 212844-53-6
Synonyms: NG-60 (Standard)
Research Areas:  

Cancer

Purvalanol A (Standard) is the analytical standard of Purvalanol A. This product is intended for research and analytical applications. Purvalanol A is a potent CDK inhibitor, which inhibits cdc2-cyclin B, cdk2-cyclin A, cdk2-cyclin E, cdk4-cyclin D1, and cdk5-p35 with IC50s of 4, 70, 35, 850, 75 nM, resepctively.
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Cat. No.: HY-136219
CAS No.: 2098621-90-8
Target:  

Fluorescent Dye

Research Areas:  

Others

Protein kinase affinity probe 1 is a novel protein kinase affinity probe for the functional identification of protein kinases (PKs). Protein kinase affinity probe 1 is a modified Purvalanol B (HY-18299) probe with 50% beads loading (Compound S3) .
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