1 Result for "

REGN7999

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "REGN7999" in MCE Product Catalog:

Cat. No.: HY-P991637
CAS No.: 2996101-49-4
Synonyms: REGN7999
Target:  

Ser/Thr Protease

Research Areas:  

Metabolic Disease

REGN7999 is a monoclonal antibody that inhibits TMPRSS6. REGN7999 inhibits TMPRSS6 activity, preventing Hemojuvelin (HJV) lysis, thereby enhancing BMP6-HJV signaling and increasing serum hepcidin. REGN7999 ameliorates iron overload and impaired erythropoiesis in a β-thalassemia mouse model by inhibiting TMPRSS6 activity. REGN7999 is indicated for research in β-thalassemia .
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