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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
8 Results for "
RXR agonist 1
" in MedChemExpress (MCE) Product Catalog:
Products (8)
8 Results for "RXR agonist 1" in MCE Product Catalog:
Cat. No.: HY-162162
CAS No.: 3033207-97-2
Target:
Research Areas:
RXR agonist 1 (Compound 33) is a highly selective RXR agonist, with EC50s of 9 nM, 18 nM, and 11 nM for RXRα, RXRβ, and RXRγ, respectively. RXR agonist 1 binds to RXR with high affinity (Kd = 0.03 μM) .
3
3 Cited Publications
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Research Areas:
CD3254 a potent and selective retinoid-X-receptor (RXR) agonist .
MM11253 is a potent and selective RARγ antagonist with an IC50 of 44 nM. MM11253 has lower inhibition of RARα, RARβ and RXRα. MM11253 blocks the growth inhibitory effects of RARγ-selective agonists .
Cat. No.: HY-180576
CAS No.: 2231746-53-3
Research Areas:
Nurr1/RXR dual agonist 1 is a dual activator of Nurr1 (EC50 = 2.6 µM) and RXR with K s of 0.6 and 1.1 µM, respectively. Nurr1/RXR dual agonist 1 exclusively activates the heterodimer response element DR5 by selectively destabilizing the Nurr1 homodimer and stabilizing the Nurr1:RXR heterodimer. Nurr1/RXR dual agonist 1 enhances expression of a specific subset of neuroprotective Nurr1 target genes while avoiding induction of genes associated with potential off-target effects in neuronal cells. Nurr1/RXR dual agonist 1 can be used for neurodegenerative diseases research .
Cat. No.: HY-N2992
CAS No.: 176390-68-4
Category:
Other Terpenoids Terpenoids Polyporaceae Poria cocos Plants Disease Research Fields Cancer
Target:
Cat. No.: HY-107399R
CAS No.: 196961-43-0
Target:
Research Areas:
CD3254 (Standard) is the analytical standard of CD3254 (HY-107399). This product is intended for research and analytical applications. CD3254 a potent and selective retinoid-X-receptor (RXR) agonist .
Cat. No.: HY-108530R
CAS No.: 345952-44-5
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Research Areas:
MM11253 (Standard) is the analytical standard of MM11253 (HY-108530). This product is intended for research and analytical applications. MM11253 is a potent and selective RARγ antagonist with an IC50 of 44 nM. MM11253 has lower inhibition of RARα, RARβ and RXRα. MM11253 blocks the growth inhibitory effects of RARγ-selective agonists .
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Protocols
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