3033207-97-2
Chemical Structure
RXR agonist 1
- CAS No.: 3033207-97-2
- Formula:C18H20ClN3O3
- Molecular Weight:361.82
InChIKey: YHIRVAZNBUWSQH-UHFFFAOYSA-N
SMILES: CC1(C)CCN(C2=CC(Cl)=NC(OCCC(O)=O)=N2)C3=C1C=CC=C3
Biological Activity: RXR agonist 1 (Compound 33) is a highly selective RXR agonist, with EC50s of 9 nM, 18 nM, and 11 nM for RXRα, RXRβ, and RXRγ, respectively. RXR agonist 1 binds to RXR with high affinity (Kd = 0.03 μM)[1].
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RXR agonist 1 | RXR agonist 1 (Compound 33) is a highly selective RXR agonist, with EC50s of 9 nM, 18 nM, and 11 nM for RXRα, RXRβ, and RXRγ, respectively. RXR agonist 1 binds to RXR with high affinity (Kd = 0.03 μM). | |||||||||||||||||||||
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Keywords