1. Metabolic Enzyme/Protease
  2. RAR/RXR
  3. CD3254

CD3254 

Cat. No.: HY-107399
Handling Instructions

CD3254 a potent and selective retinoid-X-receptor (RXR) agonist.

For research use only. We do not sell to patients.

CD3254 Chemical Structure

CD3254 Chemical Structure

CAS No. : 196961-43-0

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Description

CD3254 a potent and selective retinoid-X-receptor (RXR) agonist[1].

IC50 & Target

RXR

 

In Vitro

CD3254 induces similar phenotypes of malformations after 5 days exposure at low concentration (20 μg/L) to those after the 1st d exposure at high concentrations (50 and 100 μg/L)[1].

Cell Viability Assay[1]

Cell Line: zebrafish (Danio rerio) embryos
Concentration: 10, 20, 50, 100 μg/L
Incubation Time:
Result: The percent of survival decreased by 19.1 % in 100 μg/L CD3254-treated group after the 1st day exposure. The embryos did not hatch in groups exposed to 100 μg/L CD3254 for 5 days or to 1 mg/L CD3254 for the 1st day.
Molecular Weight

364.48

Formula

C₂₄H₂₈O₃

CAS No.

196961-43-0

SMILES

CC1(C2=CC(C3=CC(/C=C\C(O)=O)=CC=C3O)=C(C)C=C2C(C)(C)CC1)C

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

References
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Keywords:

CD3254CD 3254CD-3254RAR/RXRRetinoic acid receptorsRetinoid X receptorsRXRzebrafishembryos,Inhibitorinhibitorinhibit

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CD3254
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