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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
75 Results for "
S-adenosyl
" in MedChemExpress (MCE) Product Catalog:
Products (75)
75 Results for "S-adenosyl" in MCE Product Catalog:
24
24 Publications Verification
Cat. No.: HY-B0617
CAS No.: 29908-03-0
Synonyms: S-adenosyl methionine; Ademetionine; AdoMet
Category:
Human Gut Microbiota Metabolites Natural Products Microorganisms Neurological Disease Endogenous metabolite Disease Research Fields Inflammation/Immunology
Target:
23
23 Cited Publications
Cat. No.: HY-W017770
CAS No.: 97540-22-2
Synonyms: Ademetionine disulfate tosylate; S-adenosyl methionine disulfate tosylate; AdoMet disulfate tosylate
Target:
22
22 Cited Publications
Cat. No.: HY-B0617A
CAS No.: 52248-03-0
Synonyms: S-adenosyl methionine tosylate; Ademetionine tosylate; AdoMet tosylate
Category:
Natural Products Neurological Disease Endogenous metabolite Disease Research Fields Inflammation/Immunology
Target:
19
19 Cited Publications
Synonyms: EPZ019997 dihydrochloride
Target:
Research Areas:
GSK3368715 dihydrochloride (EPZ019997 dihydrochloride) is an orally active, reversible, and S-adenosyl-L-methionine (SAM) uncompetitive type I protein arginine methyltransferases (PRMTs) inhibitor (IC50=3.1 nM (PRMT1), 48 nM (PRMT3), 1148 nM (PRMT4), 5.7 nM (PRMT6), 1.7 nM (PRMT8)). GSK3368715 dihydrochloride (EPZ019997 dihydrochloride) produces a shift in arginine methylation states, alters exon usage, and has strong anti-cancer activity .
19
Target:
Research Areas:
GSK3368715 (EPZ019997) is an orally active, reversible, and S-adenosyl-L-methionine (SAM) uncompetitive type I protein arginine methyltransferases (PRMTs) inhibitor (IC50=3.1 nM (PRMT1), 48 nM (PRMT3), 1148 nM (PRMT4), 5.7 nM (PRMT6), 1.7 nM (PRMT8)). GSK3368715 (EPZ019997) produces a shift in arginine methylation states, alters exon usage, and has strong anti-cancer activity .
19
19 Cited Publications
Synonyms: S-adenosyl methionine iodide; Ademetionine iodide; AdoMet iodide
Target:
11
11 Cited Publications
Synonyms: S-adenosyl methionine chloride dihydrochloride; Ademetionine chloride dihydrochloride; AdoMet chloride dihydrochloride
Target:
Research Areas:
S-Adenosyl-L-methionine (S-Adenosyl methionine) chloride dihydrochloride is an orally active methyl group donor. S-Adenosyl-L-methionine chloride dihydrochloride is a dietary supplement with potent antidepressant effects. S-Adenosyl-L-methionine chloride dihydrochloride also has anti‑proliferative, pro‑apoptotic and anti‑metastatic roles in cancers. S-Adenosyl-L-methionine chloride dihydrochloride has the potential for, cancer, liver disease and osteoarthritis research .
11
Target:
Research Areas:
Cycloleucine is a specific inhibitor of S-adenosyl-methionine mediated methylation. Cycloleucine is antagonist of NMDA receptor associated glycine receptor, with a Ki of 600 μM. Cycloleucine is also a competitive inhibitor of ATP: L-methionine-S-adenosyl transferase in vitro. Cycloleucine has anxiolytic and cytostatic effects .
6
6 Cited Publications
Synonyms: Methylglyoxal-bis(guanylhydrazone); MGBG; Methyl-GAG
Mitoguazone (Methylglyoxal-bis(guanylhydrazone)) is a synthetic polycarbonyl derivative with potent antineoplastic activity. Mitoguazone is a brain-penetrant and competitive S-adenosyl-methionine decarboxylase (SAMDC) inhibitor that disrupts polyamine biosynthesis. Mitoguazone induces cell apoptosis. Mitoguazone inhibits HIV DNA integration into the cellular DNA in both monocytes and macrophages. Mitoguazone has the potential for acute leukemia, Hodgkin's and non-Hodgkin's lymphoma treatment .
5
5 Cited Publications
Cat. No.: HY-150964S
Synonyms: S-adenosyl methionine-d3 methylbenzenesulfonate; Ademetionine-d3 methylbenzenesulfonate; AdoMet-d3 methylbenzenesulfonate
3
3 Cited Publications
Target:
Research Areas:
JQEZ5 is a potent and selective EZH2 lysine methyltransferase inhibitor. JQEZ5 SAM-competitively inhibits polycomb repressive complex 2 (PRC2) with an IC50 of 80 nM. JQEZ5 has anti-tumor effects .
1
1 Cited Publications
Research Areas:
AGI-41998 is a potent and orally active inhibitor of methionine adenosyltransferase 2A (MAT2A) that effectively penetrates the blood-brain barrier. AGI-41998 exhibits inhibitory activities against MAT2A and S-adenosyl methionine (SAM) in HCT-116 MTAP-null cells with IC50s of 22 nM and 34 nM. AGI-41998 can significantly inhibit the proliferation of HCT-116 cells and tumor growth. AGI-41998 can be used to study the role of SAM regulation in the central nervous system (CNS) and colon cancer .
Cat. No.: HY-B0617S
CAS No.: 68684-40-2
Synonyms: S-adenosyl methionine-d3; Ademetionine-d3; AdoMet-d3
Cat. No.: HY-W040329
CAS No.: 958-09-8
Cat. No.: HY-B0617S2
Synonyms: S-adenosyl methionine-13C dihydrochloride; Ademetionine-13C dihydrochloride; AdoMet-13C dihydrochloride
Target:
Research Areas:
Allylic-SAM is an S-adenosyl methionine (SAM) analog. Allylic-SAM can be for the enrichment and detection of methyltransferase target sites in RNA .
Cat. No.: HY-B0617S1
CAS No.: 74084-24-5
Synonyms: S-adenosyl methionine-13C; Ademetionine-13C; AdoMet-13C
Cat. No.: HY-126126
CAS No.: 17176-17-9
Target:
Cat. No.: HY-W011683
CAS No.: 16373-93-6
Cat. No.: HY-B0617AR
CAS No.: 52248-03-0
Synonyms: S-adenosyl methionine tosylate (Standard); Ademetionine tosylate (Standard); AdoMet tosylate (Standard)
Category:
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
