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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
56 Results for "
SHIV C2/1
" in MedChemExpress (MCE) Product Catalog:
Products (56)
56 Results for "SHIV C2/1" in MCE Product Catalog:
6
6 Publications Verification
Synonyms: AT2 receptor agonist C21
Research Areas:
Cardiovascular Disease Neurological Disease Inflammation/Immunology
Buloxibutid (AT2 receptor agonist C21) is an orally active, selective angiotensin II type 2 receptor (AT2R) agonist, with a Ki value of 0.4 nM for porcine AT2R. Buloxibutid exerts effects such as vasodilation, anti-inflammation, anti-fibrosis (promoting the expression of collagenase MMP-13) and tissue repair mainly by activating the NO/cGMP pathway, inhibiting the pro-proliferative MAPK signaling, and suppressing the pro-fibrotic TGF-β/Smad pathway as well as the inflammatory NF-κB pathway. Buloxibutid can be used in research related to idiopathic pulmonary fibrosis, hypertension, and systemic sclerosis .
1
1 Cited Publications
Cat. No.: HY-N1983
CAS No.: 38395-02-7
1
Target:
Cat. No.: HY-N2103
CAS No.: 191729-43-8
Target:
Cat. No.: HY-N1375
CAS No.: 84745-94-8
Category:
Monophenols Asclepiadaceae Phenols Cynanchum otophyllum Schneid． Plants Disease Research Fields Cancer Steroids
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Cat. No.: HY-N2102
CAS No.: 191729-44-9
Target:
Cat. No.: HY-P99584
CAS No.: 914257-21-9
Synonyms: KD-247
Cat. No.: HY-156701
CAS No.: 1428988-21-9
Research Areas:
BAY-1128688 is a potent, orally active and selective AKR1C3 inhibitor with IC50 < 2 nM. BAY-1128688 shows high selectivity over related AKR1C enzymes (1C1, 1C2, 1C4) and AKR1D1. BAY-1128688 exhibits no relevant activity at major nuclear hormone receptors. BAY-1128688 reduces endometriotic lesions in the marmoset monkey endometriosis model. BAY-1128688 can be used for endometriosis research .
Cat. No.: HY-N1983R
CAS No.: 38395-02-7
Cat. No.: HY-N0420S3
CAS No.: 79864-95-2
Synonyms: Wormwood acid-13C2
Category:
Target:
Cat. No.: HY-124486
CAS No.: 21170-34-3
Target:
Research Areas:
NSC-88915 is an inhibitor of Tdp1 with an IC50 of 7.7 μM. NSC-88915 is a C21-subsitited progesterone derivative .
Cat. No.: HY-132271
CAS No.: 23214-93-9
Category:
Target:
Cat. No.: HY-Y0383S2
CAS No.: 432028-02-9
Cat. No.: HY-N0582
CAS No.: 106758-54-7
Category:
Neurological Disease Anti-aging Asclepiadaceae Cynanchum otophyllum Schneid． Plants Disease Research Fields Steroids
Target:
Cat. No.: HY-W779002
CAS No.: 261728-61-4
Cat. No.: HY-113405R
CAS No.: 641-77-0
Category:
Cat. No.: HY-N0581
CAS No.: 106644-33-1
Target:
Cat. No.: HY-N12720
CAS No.: 1800029-53-1
Category:
Apocynaceae Cardiacglycosides Plants Vincetoxicum atratum (Bunge) Morren et Decne. Steroids
Target:
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
