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Results for "

SIV

" in MedChemExpress (MCE) Product Catalog:

15

Inhibitors & Agonists

1

Peptides

1

Inhibitory Antibodies

1

Natural
Products

3

Recombinant Proteins

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-15355
    Loviride

    R 89439

    		 Reverse Transcriptase HIV Infection
    Loviride (R 89439) is a non-nucleoside reverse transcriptase inhibitor (NNRTI), with an IC50 of 0.3 µM for reverse transcriptase from HIV-1. Loviride (R 89439) inhibits HIV-1, HIV-2 and SIV replication in MT-4 cells .
    Loviride
  • HY-171860
    FC-14369

    		PROTACs HIV Infection Cancer
    FC-14369 is a PROTAC degrader targeting the HIV-1 Nef protein, with a DC50 value of 160 nM. Through its bifunctional structure, FC-14369 binds to Nef and the Cereblon E3 ubiquitin ligase, induces Nef ubiquitination and proteasomal degradation, restores the expression of cell-surface CD4 and MHC-I, and inhibits HIV-1 replication. FC-14369 can be used in research on HIV infection and AIDS. FC-14369 is applicable to studies related to HIV-1 infection .
    FC-14369
  • HY-105448
    U-75875

    		HIV Protease Infection
    U-75875 is a HIV-1 protease inhibitor. U-75875 can block Gag-Pol protein processing and viral maturation and replication. U-75875 can be used for the research of infection .
    U-75875
  • HY-171862
    Nef ligand-2

    		HIV Ligands for Target Protein for PROTAC Infection
    Nef ligand-2 is a binder of Nef. Nef ligand-2 is Ligands for E3 Ligase. Nef ligand-2 is the Nef Binder portion of FC-14369 (HY-171860) .
    Nef ligand-2
  • HY-15355R
    Loviride (Standard)

    R 89439 (Standard)

    		 Reverse Transcriptase HIV Reference Standards Infection
    Loviride (Standard) is the analytical standard of Loviride. This product is intended for research and analytical applications. Loviride (R 89439) is a non-nucleoside reverse transcriptase inhibitor (NNRTI), with an IC50 of 0.3 μM for reverse transcriptase from HIV-1. Loviride (R 89439) inhibits HIV-1, HIV-2 and SIV replication in MT-4 cells .
    Loviride (Standard)
  • HY-P991655
    AGS-009

    		IFNAR HIV Infection Inflammation/Immunology
    AGS-009 is a humanized monoclonal neutralising antibody targeting IFN-α. AGS-009 significantly reduces activated lymphocytes, such as CD4 + and CD8 + T cells as well as B cells in SIV infection rhesus macaque models. AGS-009 can be used for autoimmune diseases like systemic lupus erythematosus (SLE) and HIV infections research .
    AGS-009
  • HY-105394
    BEA 005

    		HIV Infection
    BEA 005 is an antivirus agent. BEA 005 can block early systemic and mucosal infections with SIV and HIV-2 .
    BEA 005
  • HY-125148
    AQ148

    		HIV Protease Infection
    AQ148 is a HIV-1 protease inhibitor (Ki=137 nM). The IC50 values ??of AQ148 for the inhibition of HIV-1, HIV-2 and SIV aspartic proteases are 1.5 μM, 3.4 μM and 5 μM, respectively .
    AQ148
  • HY-P10801
    mC46 peptide

    C46 peptide

    		 HIV Infection
    mC46 (C46) peptide is a membrane-associated fusion peptide inhibitor. mC46 peptide potently inhibits HIV-1 replication and entry. mC46 also inhibits CCR5-tropic, CXCR4-tropic, and dual-tropic HIVs, SIV, and SHIV .
    mC46 peptide
  • HY-106971
    PD 161374

    		HIV Infection
    PD 161374 is an inhibitor targeting the HIV-1 nucleocapsid protein NCp7. PD 161374 primarily acts on the early stages of viral replication, inhibiting the completion of reverse transcription without affecting viral entry or later assembly. PD 161374 remains active against HIV-1, HIV-2, SIV, and drug-resistant strains. PD 161374 can be used to study antiretroviral agents .
    PD 161374
  • HY-134809A
    Cyclotriazadisulfonamide hydrochloride

    CADA hydrochloride

    		 HIV Infection
    Cyclotriazadisulfonamide (CADA) hydrochloride is a specific CD4-targeted HIV entry inhibitor with activity against HIV-1 replication. Cyclotriazadisulfonamide hydrochloride can specifically downregulate the expression of CD4 receptors on the cell surface, effectively inhibiting HIV transmission. Cyclotriazadisulfonamide hydrochloride can inhibit HIV-1(NL4.3) and SIV(mac251), and has a synergistic effect when used in combination with cellulose acetate (CAP). Cyclotriazadisulfonamide hydrochloride can also be used as a microbial gel formulation to maintain CD4 downregulation and antiviral activity, and is a broad-spectrum anti-HIV agent.
    Cyclotriazadisulfonamide hydrochloride
  • HY-W090073
    1,3-Di-2-thienylthieno[3,4-c][1,2,5]thiadiazole-2-SIV

    4,6-Di(2-thienyl)thieno[3,4-c][1,2,5]thiadiazole

    		 MOFs Others
    1,3-Di-2-thienylthieno[3,4-c][1,2,5]thiadiazole-2-SIV (4,6-Di(2-thienyl)thieno[3,4-c][1,2,5]thiadiazole) is a metal-organic framework (MOF).
    1,3-Di-2-thienylthieno[3,4-c][1,2,5]thiadiazole-2-SIV
  • HY-182474
    INDOPY-1

    Indolopyridone-1

    		 Reverse Transcriptase DNA/RNA Synthesis HIV Infection
    INDOPY-1 (Indolopyridone-1) is a selective, reversible, and competitive HIV-1 reverse transcriptase inhibitor. INDOPY-1 reversibly binds to the active site of reverse transcriptase. INDOPY-1 inhibits DNA synthesis. INDOPY-1 exhibits antiviral activity against various retroviruses, including HIV-1 IIIB, HIV-1 HXB2 K103N Y181C, HIV-2 ROD, and SIV Mac251. INDOPY-1 can be used in the research of immunodeficiency virus infection .
    INDOPY-1
  • HY-N16734
    Norviburtinal

    		Others Cancer
    Norviburtinal is a non-selective cytotoxic and pro-angiogenic agent. Norviburtinal has an IC50 of 3.25 μg/mL on G361 melanoma cells and an effective concentration of 50 μg/mL on zebrafish embryos. Norviburtinal promotes capillary sprout formation in zebrafish subintestinal vessels (SIV) and has both cytotoxic and pro-angiogenic activities. Norviburtinal can be used in research on promoting angiogenesis related to melanoma, lung cancer, and wound healing .
    Norviburtinal
  • HY-183663
    PD-159206

    		HIV Infection
    PD-159206 is an anti-HIV agent. PD-159206 inhibits early pre-integration steps of the HIV life cycle, and delays sequential progression of reverse transcription products. PD-159206 can be used for the research of HIV infection .
    PD-159206

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