18 Results for "

SIV

" in MedChemExpress (MCE) Product Catalog:
Products (18)

18 Results for "SIV" in MCE Product Catalog:

Cat. No.: HY-15355
CAS No.: 147362-57-0
Purity:  99.59%
Synonyms: R 89439
Research Areas:  

Infection

Loviride (R 89439) is a non-nucleoside reverse transcriptase inhibitor (NNRTI), with an IC50 of 0.3 µM for reverse transcriptase from HIV-1. Loviride (R 89439) inhibits HIV-1, HIV-2 and SIV replication in MT-4 cells .
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Cat. No.: HY-171860
CAS No.: 3066894-28-5
Target:  

PROTACs HIV

Research Areas:  

Infection Cancer

FC-14369 is a PROTAC degrader targeting the HIV-1 Nef protein, with a DC50 value of 160 nM. Through its bifunctional structure, FC-14369 binds to Nef and the Cereblon E3 ubiquitin ligase, induces Nef ubiquitination and proteasomal degradation, restores the expression of cell-surface CD4 and MHC-I, and inhibits HIV-1 replication. FC-14369 can be used in research on HIV infection and AIDS. FC-14369 is applicable to studies related to HIV-1 infection .
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Cat. No.: HY-105448
CAS No.: 112190-24-6
Target:  

HIV Protease

Research Areas:  

Infection

U-75875 is a HIV-1 protease inhibitor. U-75875 can block Gag-Pol protein processing and viral maturation and replication. U-75875 can be used for the research of infection .
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Cat. No.: HY-171862
CAS No.: 3066896-28-1
Research Areas:  

Infection

Nef ligand-2 is a binder of Nef. Nef ligand-2 is Ligands for E3 Ligase. Nef ligand-2 is the Nef Binder portion of FC-14369 (HY-171860) .
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Cat. No.: HY-15355R
CAS No.: 147362-57-0
Synonyms: R 89439 (Standard)
Research Areas:  

Infection

Loviride (Standard) is the analytical standard of Loviride. This product is intended for research and analytical applications. Loviride (R 89439) is a non-nucleoside reverse transcriptase inhibitor (NNRTI), with an IC50 of 0.3 μM for reverse transcriptase from HIV-1. Loviride (R 89439) inhibits HIV-1, HIV-2 and SIV replication in MT-4 cells .
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Cat. No.: HY-P991655

Target:  

IFNAR HIV

Research Areas:  

Infection Inflammation/Immunology

AGS-009 is a humanized monoclonal neutralising antibody targeting IFN-α. AGS-009 significantly reduces activated lymphocytes, such as CD4 + and CD8 + T cells as well as B cells in SIV infection rhesus macaque models. AGS-009 can be used for autoimmune diseases like systemic lupus erythematosus (SLE) and HIV infections research .
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Cat. No.: HY-105394
CAS No.: 132235-73-5
Target:  

HIV

Research Areas:  

Infection

BEA 005 is an antivirus agent. BEA 005 can block early systemic and mucosal infections with SIV and HIV-2 .
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Cat. No.: HY-125148
CAS No.: 178820-70-7
Target:  

HIV Protease

Research Areas:  

Infection

AQ148 is a HIV-1 protease inhibitor (Ki=137 nM). The IC50 values ??of AQ148 for the inhibition of HIV-1, HIV-2 and SIV aspartic proteases are 1.5 μM, 3.4 μM and 5 μM, respectively .
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Cat. No.: HY-P10801
Synonyms: C46 peptide
Target:  

HIV

Research Areas:  

Infection

mC46 (C46) peptide is a membrane-associated fusion peptide inhibitor. mC46 peptide potently inhibits HIV-1 replication and entry. mC46 also inhibits CCR5-tropic, CXCR4-tropic, and dual-tropic HIVs, SIV, and SHIV .
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Cat. No.: HY-106971
CAS No.: 177785-47-6
Target:  

HIV

Research Areas:  

Infection

PD 161374 is an inhibitor targeting the HIV-1 nucleocapsid protein NCp7. PD 161374 primarily acts on the early stages of viral replication, inhibiting the completion of reverse transcription without affecting viral entry or later assembly. PD 161374 remains active against HIV-1, HIV-2, SIV, and drug-resistant strains. PD 161374 can be used to study antiretroviral agents .
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Cat. No.: HY-134809A
CAS No.: 392287-03-5
Synonyms: CADA hydrochloride
Target:  

HIV

Research Areas:  

Infection

Cyclotriazadisulfonamide (CADA) hydrochloride is a specific CD4-targeted HIV entry inhibitor with activity against HIV-1 replication. Cyclotriazadisulfonamide hydrochloride can specifically downregulate the expression of CD4 receptors on the cell surface, effectively inhibiting HIV transmission. Cyclotriazadisulfonamide hydrochloride can inhibit HIV-1(NL4.3) and SIV(mac251), and has a synergistic effect when used in combination with cellulose acetate (CAP). Cyclotriazadisulfonamide hydrochloride can also be used as a microbial gel formulation to maintain CD4 downregulation and antiviral activity, and is a broad-spectrum anti-HIV agent.
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Cat. No.: HY-W090073
CAS No.: 150600-72-9
Synonyms: 4,6-Di(2-thienyl)thieno[3,4-c][1,2,5]thiadiazole
Target:  

MOFs

Research Areas:  

Others

1,3-Di-2-thienylthieno[3,4-c][1,2,5]thiadiazole-2-SIV (4,6-Di(2-thienyl)thieno[3,4-c][1,2,5]thiadiazole) is a metal-organic framework (MOF).
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Cat. No.: HY-182474
CAS No.: 352548-47-1
Synonyms: Indolopyridone-1
Research Areas:  

Infection

INDOPY-1 (Indolopyridone-1) is a selective, reversible, and competitive HIV-1 reverse transcriptase inhibitor. INDOPY-1 reversibly binds to the active site of reverse transcriptase. INDOPY-1 inhibits DNA synthesis. INDOPY-1 exhibits antiviral activity against various retroviruses, including HIV-1 IIIB, HIV-1 HXB2 K103N Y181C, HIV-2 ROD, and SIV Mac251. INDOPY-1 can be used in the research of immunodeficiency virus infection .
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Cat. No.: HY-P75159
Purity:  ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: Simian immunodeficiency virus (SIV) (isolate 216.94.A2) gp120 Protein
Species:  
Source:  
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Cat. No.: HY-P75248
Purity:  ≥ 85%, as determined by reducing SDS-PAGE.
Synonyms: Simian immunodeficiency virus (SIV) (isolate F236) envelope glycoprotein gp120 Protein
Species:  
Source:  
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Cat. No.: HY-P75249
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: Simian immunodeficiency virus (SIV) (isolate SIVmac251v31523ru28) envelope glycoprotein gp120 Protein
Species:  
Source:  
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Cat. No.: HY-N16734
CAS No.: 85051-41-8
Norviburtinal is a non-selective cytotoxic and pro-angiogenic agent. Norviburtinal has an IC50 of 3.25 μg/mL on G361 melanoma cells and an effective concentration of 50 μg/mL on zebrafish embryos. Norviburtinal promotes capillary sprout formation in zebrafish subintestinal vessels (SIV) and has both cytotoxic and pro-angiogenic activities. Norviburtinal can be used in research on promoting angiogenesis related to melanoma, lung cancer, and wound healing .
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Cat. No.: HY-183663
CAS No.: 171744-42-6
Target:  

HIV

Research Areas:  

Infection

PD-159206 is an anti-HIV agent. PD-159206 inhibits early pre-integration steps of the HIV life cycle, and delays sequential progression of reverse transcription products. PD-159206 can be used for the research of HIV infection .
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